TY - JOUR
T1 - Detection of Five Components Having Antibody Activity in Rat Antisera
AU - Banovitz, Jay
AU - Ishizaka, Kimishige
N1 - Funding Information:
This work was supported by USPHS Research Grants AI-05840, AI-07613 and AI-04985.
PY - 1967/5
Y1 - 1967/5
N2 - By radioimmunoelectrophoresis, antibodies associated with γ1, γ2 and γM globulins and 2 unidentified components, U1 and U2, were detected in rat antisera to BSA and BGG. When rats were immunized with these antigens adsorbed to bentonite or included in complete Freund's adjuvant, the sequence of the immune response in rats involves first the formation of γ1 antibody followed upon further immunization by γ2 antibody. Generally, γM and the unknown components, U1 and U2, only appeared in hyperimmune sera.
AB - By radioimmunoelectrophoresis, antibodies associated with γ1, γ2 and γM globulins and 2 unidentified components, U1 and U2, were detected in rat antisera to BSA and BGG. When rats were immunized with these antigens adsorbed to bentonite or included in complete Freund's adjuvant, the sequence of the immune response in rats involves first the formation of γ1 antibody followed upon further immunization by γ2 antibody. Generally, γM and the unknown components, U1 and U2, only appeared in hyperimmune sera.
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U2 - 10.3181/00379727-125-32018
DO - 10.3181/00379727-125-32018
M3 - Article
C2 - 4165488
AN - SCOPUS:0014082220
SN - 0037-9727
VL - 125
SP - 78
EP - 82
JO - Proceedings of the Society for Experimental Biology and Medicine
JF - Proceedings of the Society for Experimental Biology and Medicine
IS - 1
ER -