Detection of Five Components Having Antibody Activity in Rat Antisera

Jay Banovitz, Kimishige Ishizaka

Research output: Contribution to journalArticlepeer-review

Abstract

By radioimmunoelectrophoresis, antibodies associated with γ1, γ2 and γM globulins and 2 unidentified components, U1 and U2, were detected in rat antisera to BSA and BGG. When rats were immunized with these antigens adsorbed to bentonite or included in complete Freund's adjuvant, the sequence of the immune response in rats involves first the formation of γ1 antibody followed upon further immunization by γ2 antibody. Generally, γM and the unknown components, U1 and U2, only appeared in hyperimmune sera.

Original languageEnglish (US)
Pages (from-to)78-82
Number of pages5
JournalProceedings of the Society for Experimental Biology and Medicine
Volume125
Issue number1
DOIs
StatePublished - May 1967

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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