Detection of feedback in the central nervous system using system identification techniques

S. M. Schnider, R. H. Kwong, Frederick Lenz, H. C. Kwan

Research output: Contribution to journalArticle

Abstract

An analysis method to detect the presence of feedback between biological signals, particularly those associated with the central nervous system, is presented. The technique is based on recent results in the system identification literature involving the concept of a feedback free process. It may be applied to volume conducted signals such as EEG and EMG, as well as to neuronal spike trains through the use of a data transformation procedure. The utility of the technique is then demonstrated in a study of the relationship between Parkinsonian tremor and certain tremor cells found in the thalamus of Parkinsonian patients, using data collected during thalamotomies. The results obtained suggest that feedback mechanisms may be an important factor contributing to Parkinsonian tremor.

Original languageEnglish (US)
Pages (from-to)203-212
Number of pages10
JournalBiological Cybernetics
Volume60
Issue number3
DOIs
StatePublished - Jan 1989
Externally publishedYes

Fingerprint

Neurology
Tremor
Identification (control systems)
Central Nervous System
Feedback
Electroencephalography
Thalamus

ASJC Scopus subject areas

  • Biophysics

Cite this

Detection of feedback in the central nervous system using system identification techniques. / Schnider, S. M.; Kwong, R. H.; Lenz, Frederick; Kwan, H. C.

In: Biological Cybernetics, Vol. 60, No. 3, 01.1989, p. 203-212.

Research output: Contribution to journalArticle

Schnider, S. M. ; Kwong, R. H. ; Lenz, Frederick ; Kwan, H. C. / Detection of feedback in the central nervous system using system identification techniques. In: Biological Cybernetics. 1989 ; Vol. 60, No. 3. pp. 203-212.
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