DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS.

S. M. Schnider, R. H. Kwong, H. C. Kwan, Frederick Lenz

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Closed-loop system identification techniques are applied to signals obtained from the central nervous system of human Parkinsonian patients. The question is posed as to whether feedback exists from tremor, via sensory inputs, to thalamic tremor cells which are thought to drive Parkinsonian tremor. Linear multivariable models are fitted to the data, and it is found that, in general, the relationship between tremor and cell activity is best described by a closed-loop system. The results are consistent with the hypothesis that Parkinsonian tremor is the result of an unstable reflex loop in the central nervous system. 16 refs.

Original languageEnglish (US)
Title of host publicationProceedings of the IEEE Conference on Decision and Control
PublisherIEEE
Pages291-294
Number of pages4
StatePublished - 1986
Externally publishedYes

Fingerprint

Neurology
Closed loop systems
Feedback
Identification (control systems)

ASJC Scopus subject areas

  • Chemical Health and Safety
  • Control and Systems Engineering
  • Safety, Risk, Reliability and Quality

Cite this

Schnider, S. M., Kwong, R. H., Kwan, H. C., & Lenz, F. (1986). DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS. In Proceedings of the IEEE Conference on Decision and Control (pp. 291-294). IEEE.

DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS. / Schnider, S. M.; Kwong, R. H.; Kwan, H. C.; Lenz, Frederick.

Proceedings of the IEEE Conference on Decision and Control. IEEE, 1986. p. 291-294.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Schnider, SM, Kwong, RH, Kwan, HC & Lenz, F 1986, DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS. in Proceedings of the IEEE Conference on Decision and Control. IEEE, pp. 291-294.
Schnider SM, Kwong RH, Kwan HC, Lenz F. DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS. In Proceedings of the IEEE Conference on Decision and Control. IEEE. 1986. p. 291-294
Schnider, S. M. ; Kwong, R. H. ; Kwan, H. C. ; Lenz, Frederick. / DETECTION OF FEEDBACK IN THE CENTRAL NERVOUS SYSTEM OF PARKINSONIAN PATIENTS. Proceedings of the IEEE Conference on Decision and Control. IEEE, 1986. pp. 291-294
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