Detection of cavernous transformation of the portal vein by contrast-enhanced ultrasound

Misun Hwang, Matthew A. Thimm, Anthony L Guerrerio

Research output: Contribution to journalArticle

Abstract

Purpose: Cavernous transformation of the portal vein can be missed on color Doppler exam or arterial phase cross-sectional imaging due to their slow flow and delayed enhancement. Contrast-enhanced ultrasound (CEUS) offers many advantages over other imaging techniques and can be used to successfully detect cavernous transformations of the portal vein. Methods: A 10-month-old female was followed for repeat episodes of hematemesis. Computed tomography angiography (CTA) and magnetic resonance arteriogram (MRA) and portal venography were performed. Color Doppler exam of the portal vein was performed followed by administration of Lumason, a microbubble US contrast agent. Results: Magnetic resonance arteriogram, CTA, and color Doppler exam at the time of initial presentation was unremarkable without obvious vascular malformation within the limits of motion degraded exam. At 8-month follow-up, esophagogastroduodenoscopy revealed a vascular malformation in the distal esophagus which was sclerosed. At 6 month after sclerosis of the lesion, portal venography revealed occlusion of the portal vein with extensive collateralization. Color Doppler revealed subtle hyperarterialization and periportal collaterals. CEUS following color Doppler exam demonstrated extensive enhancement of periportal collaterals. Repeat color Doppler after contrast administration demonstrated extensive Doppler signal in the collateral vessels, suggestive of cavernous transformation. Conclusions: We describe a case of cavernous transformation of the portal vein missed on initial color Doppler, CTA and MRA, but detected with contrast-enhanced ultrasound technique.

Original languageEnglish (US)
Pages (from-to)153-157
Number of pages5
JournalJournal of Ultrasound
Volume21
Issue number2
DOIs
StatePublished - Jun 1 2018

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Color
Vascular Malformations
Magnetic Resonance Spectroscopy
Phlebography
Portal Vein
Digestive System Endoscopy
Hematemesis
Microbubbles
antineoplaston A10
Sclerosis
Cavernous Transformation of Portal Vein
Contrast Media
Esophagus
Computed Tomography Angiography

Keywords

  • Cavernous transformation
  • Contrast-enhanced ultrasound (CEUS)
  • Portal vein

ASJC Scopus subject areas

  • Internal Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Detection of cavernous transformation of the portal vein by contrast-enhanced ultrasound. / Hwang, Misun; Thimm, Matthew A.; Guerrerio, Anthony L.

In: Journal of Ultrasound, Vol. 21, No. 2, 01.06.2018, p. 153-157.

Research output: Contribution to journalArticle

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