Detection of amphotericin B-resistant Candida isolates in a broth-based system

J. H. Rex; C. R. Cooper; W. G. Merz; J. N. Galgiani; E. J. Anaissie

doi:10.1128/AAC.39.4.906

Detection of amphotericin B-resistant Candida isolates in a broth-based system

J. H. Rex, C. R. Cooper, W. G. Merz, J. N. Galgiani, E. J. Anaissie

Research output: Contribution to journal › Article › peer-review

178 Scopus citations

Abstract

Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolates. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a series of resistant isolates.

Original language	English (US)
Pages (from-to)	906-909
Number of pages	4
Journal	Antimicrobial agents and chemotherapy
Volume	39
Issue number	4
DOIs	https://doi.org/10.1128/AAC.39.4.906
State	Published - 1995
Externally published	Yes

ASJC Scopus subject areas

Pharmacology
Pharmacology (medical)
Infectious Diseases

Access to Document

10.1128/AAC.39.4.906

Cite this

@article{544384f7aadc4e0d8c1e8ad022c29af3,

title = "Detection of amphotericin B-resistant Candida isolates in a broth-based system",

abstract = "Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolates. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a series of resistant isolates.",

author = "Rex, {J. H.} and Cooper, {C. R.} and Merz, {W. G.} and Galgiani, {J. N.} and Anaissie, {E. J.}",

year = "1995",

doi = "10.1128/AAC.39.4.906",

language = "English (US)",

volume = "39",

pages = "906--909",

journal = "Antimicrobial agents and chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "4",

}

TY - JOUR

T1 - Detection of amphotericin B-resistant Candida isolates in a broth-based system

AU - Rex, J. H.

AU - Cooper, C. R.

AU - Merz, W. G.

AU - Galgiani, J. N.

AU - Anaissie, E. J.

PY - 1995

Y1 - 1995

N2 - Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolates. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a series of resistant isolates.

AB - Because of the limited ability of the National Committee for Clinical Laboratory Standards proposed M27P methodology to detect resistance to amphotericin B by Candida isolates, we sought to identify alternative media and pH conditions that could reliably identify resistant isolates. Antibiotic Medium 3 broth (also known as Penassay broth) buffered to pH 5 or pH 7 produced superior results and readily identified a series of resistant isolates.

UR - http://www.scopus.com/inward/record.url?scp=0028969417&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028969417&partnerID=8YFLogxK

U2 - 10.1128/AAC.39.4.906

DO - 10.1128/AAC.39.4.906

M3 - Article

C2 - 7785993

AN - SCOPUS:0028969417

SN - 0066-4804

VL - 39

SP - 906

EP - 909

JO - Antimicrobial agents and chemotherapy

JF - Antimicrobial agents and chemotherapy

IS - 4

ER -

Detection of amphotericin B-resistant Candida isolates in a broth-based system

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this