Detection and treatment of children and adolescents with dyslipidemia

Peter O. Kwiterovich

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Evidence for a causative relationship between dyslipidemia in children and adolescents and the early lesions of atherosclerosis in young adults is strong and internally consistent. Youth affected with dyslipidemia include those with single gene disorders such as familial hypercholesterolemia (FH), and those with oligogenic disorders such as familial combined hyperlipidemia (FCHL). In large populations of children followed up for several decades, the environmental and biologic contributions of elevated low-density lipoprotein (LDL) and obesity to the dyslipidemic phenotype and early subclinical atherosclerosis are impressive. Universal screening will be required for optimal detection and treatment of dyslipidemia and youth at risk for early atherosclerosis. This chapter provides an in-depth clinical and metabolic paradigm where a spectrum of dyslipidemia can be dissected and treated.

Original languageEnglish (US)
Title of host publicationDyslipidemias
Subtitle of host publicationPathophysiology, Evaluation and Management
PublisherHumana Press Inc.
Pages67-97
Number of pages31
ISBN (Electronic)9781607614241
ISBN (Print)9781607614234
DOIs
StatePublished - Jan 1 2015

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ASJC Scopus subject areas

  • Medicine(all)

Cite this

Kwiterovich, P. O. (2015). Detection and treatment of children and adolescents with dyslipidemia. In Dyslipidemias: Pathophysiology, Evaluation and Management (pp. 67-97). Humana Press Inc.. https://doi.org/10.1007/978-1-60761-424-1_5