Abstract
Analytic solutions modelling the propagation of fluorescence photons in heterogeneous turbid media are employed to generate `simulated experimental data' with realistic signal-to-noise and investigate the detectability of fluorescent objects in deep turbid media. Transmission measurements show that for a realistic fluorophore concentration and lifetime variation, the smallest detectable object is about 0.2 cm in radius assuming 1% amplitude and 0.5° phase random noise. Moreover, fluorescent diffuse photon density waves amplitude and phase data measured at the assumed conditions suggest, that for known object size, fluorophore concentration and lifetime within the object can be well characterized over a broad parameter space.
| Original language | English (US) |
|---|---|
| Number of pages | 1 |
| Journal | Conference Proceedings - Lasers and Electro-Optics Society Annual Meeting-LEOS |
| Volume | 11 |
| State | Published - Jan 1 1997 |
| Externally published | Yes |
| Event | Proceedings of the 1997 Conference on Lasers and Electro-Optics, CLEO - Baltimore, MD, USA Duration: May 18 1997 → May 23 1997 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Electrical and Electronic Engineering