@article{2262db46f0c14cc9aa4940925987601b,
title = "Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis",
abstract = "Previously identified single nucleotide polymorphisms (SNPs) in genome wide association studies (GWAS) of cardiovascular disease (CVD) in participants of mostly European descent were tested for association with subclinical cardiovascular disease (sCVD), coronary artery calcium score (CAC) and carotid intima media thickness (CIMT) in the Multi-Ethnic Study of Atherosclerosis (MESA). The data in this data in brief article correspond to the article Common Genetic Variants and Subclinical Atherosclerosis: The Multi-Ethnic Study of Atherosclerosis [1]. This article includes the demographic information of the participants analyzed in the article as well as graphical displays and data tables of the association of the selected SNPs with CAC and of the meta-analysis across ethnicities of the association of CIMT-c (common carotid), CIMT-I (internal carotid), CAC-d (CAC as dichotomous variable with CAC>0) and CAC-c (CAC as continuous variable, the log of the raw CAC score plus one) and CVD. The data tables corresponding to the 9p21 fine mapping experiment as well as the power calculations referenced in the article are also included.",
keywords = "Carotid intima-media thickness (CIMT), Common genetic variant, Coronary artery calcium (CAC), Single nucleotide polymorphism (SNP), Subclincal atherosclerosis",
author = "Vargas, {Jose D.} and Ani Manichaikul and Wang, {Xin Qun} and Rich, {Stephen S.} and Rotter, {Jerome I.} and Post, {Wendy S.} and Polak, {Joseph F.} and Budoff, {Matthew J.} and Bluemke, {David A.}",
note = "Funding Information: MESA and the MESA SHARe project are conducted and supported by contracts N01-HC-95159, N01-HC-95160, N01-HC-95161, N01-HC-95162, N01-HC-95163, N01-HC-95164, N01-HC-95165, N01-HC-95166, N01-HC-95167, N01-HC-95168, N01-HC-95169, UL1-TR-001079 and UL1-TR-000040 from the National Heart, Lung, and Blood Institute (NHLBI, http://www.nhlbi.nih.gov ). MESA Family is conducted and supported in collaboration with MESA investigators; support is provided by grants and contracts R01HL071051, R01HL071205, R01HL071250, R01HL071251, R01HL071252, R01HL071258, R01HL071259, M01-RR00425, UL1RR033176, and UL1TR000124. Funding for MESA SHARe genotyping was provided by NHLBI Contract N02‐HL‐6‐4278. The provision of genotyping data was supported in part by the National Center for Advancing Translational Sciences, CTSI grant UL1TR000124, and the National Institute of Diabetes and Digestive and Kidney Disease Diabetes Research Center (DRC) grant DK063491 to the Southern California Diabetes Endocrinology Research Center. This manuscript was approved for submission by the Presentations and Publications Committee. Publisher Copyright: {\textcopyright} 2016.",
year = "2016",
month = jun,
day = "1",
doi = "10.1016/j.dib.2016.01.048",
language = "English (US)",
volume = "7",
pages = "229--242",
journal = "Data in Brief",
issn = "2352-3409",
publisher = "Elsevier BV",
}