Desorption of ions from rat membranes: Selectivity of different ionization techniques

Catherine Fenselau, David N. Heller, James K. Olthoff, Robert J. Cotter, Yasuo Kishimoto, O. Manuel Uy

Research output: Contribution to journalArticlepeer-review

Abstract

Complex lipid biomarkers, including phosphatidylcholines, cerebrosides and sulfatides, are shown to be desorbed intact from rat brain myelin and rat liver microsomes by liquid secondary ion mass spectrometry, by plasma desorption and by laser desorption. Different polar lipids are favored by the different desorption techniques and as negative or positive ions. These selectivities support current theories about ionization for the different techniques.

Original languageEnglish (US)
Pages (from-to)1037-1045
Number of pages9
JournalBiomedical & Environmental Mass Spectrometry
Volume18
Issue number12
DOIs
StatePublished - Dec 1989

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Pollution

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