Designing dendritic frameworks using versatile building blocks suitable for CuI-catalyzed alkyne azide 'click' chemistry

Rami Hourani, Anjali Sharma, Ashok Kakkar

Research output: Contribution to journalArticle

Abstract

Synthesis of molecular building blocks that incorporate azide and alkyne-terminated functionalities suitable for CuI-catalyzed cycloaddition between alkynes and azides is reported. Their utility in constructing dendritic frameworks with 4, 6, or 12 peripheral acetylene groups using either the convergent or divergent methodology, and their functionalization with desirable end groups are demonstrated.

Original languageEnglish (US)
Pages (from-to)3792-3795
Number of pages4
JournalTetrahedron Letters
Volume51
Issue number29
DOIs
StatePublished - Jul 21 2010

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Dive into the research topics of 'Designing dendritic frameworks using versatile building blocks suitable for Cu<sup>I</sup>-catalyzed alkyne azide 'click' chemistry'. Together they form a unique fingerprint.

  • Cite this