Design of a compartmentalized shotgun assembler for the human genome

Daniel H. Huson; Knut Reinert; Saul A. Kravitz; Karin A. Remington; Art L. Delcher; Ian M. Dew; Mike Flanigan; Aaron L. Halpern; Zhongwu Lai; Clark M. Mobarry; Granger G. Sutton; Eugene W. Myers

doi:10.1093/bioinformatics/17.suppl_1.S132

Design of a compartmentalized shotgun assembler for the human genome

Daniel H. Huson, Knut Reinert, Saul A. Kravitz, Karin A. Remington, Art L. Delcher, Ian M. Dew, Mike Flanigan, Aaron L. Halpern, Zhongwu Lai, Clark M. Mobarry, Granger G. Sutton, Eugene W. Myers

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Two different strategies for determining the human genome are currently being pursued: one is the "clone-by-clone" approach, employed by the publicly funded project, and the other is the "whole genome shotgun assembler" approach, favored by researchers at Celera Genomics. An interim strategy employed at Celera, called compartmentalized shotgun assembly, makes use of preliminary data produced by both approaches. In this paper we describe the design, implementation and operation of the "compartmentalized shotgun assembler".

Original language	English (US)
Pages (from-to)	S132-S139
Journal	Bioinformatics
Volume	17
DOIs	https://doi.org/10.1093/bioinformatics/17.suppl_1.S132
State	Published - 2001
Externally published	Yes

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

Access to Document

10.1093/bioinformatics/17.suppl_1.S132

Cite this

@article{720c6e8cf4174ef8b9c23654fd488136,

title = "Design of a compartmentalized shotgun assembler for the human genome",

abstract = "Two different strategies for determining the human genome are currently being pursued: one is the {"}clone-by-clone{"} approach, employed by the publicly funded project, and the other is the {"}whole genome shotgun assembler{"} approach, favored by researchers at Celera Genomics. An interim strategy employed at Celera, called compartmentalized shotgun assembly, makes use of preliminary data produced by both approaches. In this paper we describe the design, implementation and operation of the {"}compartmentalized shotgun assembler{"}.",

author = "Huson, {Daniel H.} and Knut Reinert and Kravitz, {Saul A.} and Remington, {Karin A.} and Delcher, {Art L.} and Dew, {Ian M.} and Mike Flanigan and Halpern, {Aaron L.} and Zhongwu Lai and Mobarry, {Clark M.} and Sutton, {Granger G.} and Myers, {Eugene W.}",

year = "2001",

doi = "10.1093/bioinformatics/17.suppl_1.S132",

language = "English (US)",

volume = "17",

pages = "S132--S139",

journal = "Bioinformatics",

issn = "1367-4803",

publisher = "Oxford University Press",

}

TY - JOUR

T1 - Design of a compartmentalized shotgun assembler for the human genome

AU - Huson, Daniel H.

AU - Reinert, Knut

AU - Kravitz, Saul A.

AU - Remington, Karin A.

AU - Delcher, Art L.

AU - Dew, Ian M.

AU - Flanigan, Mike

AU - Halpern, Aaron L.

AU - Lai, Zhongwu

AU - Mobarry, Clark M.

AU - Sutton, Granger G.

AU - Myers, Eugene W.

PY - 2001

Y1 - 2001

N2 - Two different strategies for determining the human genome are currently being pursued: one is the "clone-by-clone" approach, employed by the publicly funded project, and the other is the "whole genome shotgun assembler" approach, favored by researchers at Celera Genomics. An interim strategy employed at Celera, called compartmentalized shotgun assembly, makes use of preliminary data produced by both approaches. In this paper we describe the design, implementation and operation of the "compartmentalized shotgun assembler".

AB - Two different strategies for determining the human genome are currently being pursued: one is the "clone-by-clone" approach, employed by the publicly funded project, and the other is the "whole genome shotgun assembler" approach, favored by researchers at Celera Genomics. An interim strategy employed at Celera, called compartmentalized shotgun assembly, makes use of preliminary data produced by both approaches. In this paper we describe the design, implementation and operation of the "compartmentalized shotgun assembler".

UR - http://www.scopus.com/inward/record.url?scp=0035224746&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035224746&partnerID=8YFLogxK

U2 - 10.1093/bioinformatics/17.suppl_1.S132

DO - 10.1093/bioinformatics/17.suppl_1.S132

M3 - Article

C2 - 11473002

AN - SCOPUS:0035224746

SN - 1367-4803

VL - 17

SP - S132-S139

JO - Bioinformatics

JF - Bioinformatics

ER -

Design of a compartmentalized shotgun assembler for the human genome

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this