Design and development of a co-planar fluorescence and X-ray tomograph

Juan Aguirre, Alejandro Sisniega, Jorge Ripoll, Manuel Desco, Juan José Vaquero

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Non-contact Fluorescence Diffuse Optical Tomography (FDOT) is rapidly becoming an important tool for small animal research, since it is able to display the 3D distribution of near infrared fluorescent probes in the whole body. FDOT, like other functional and molecular imaging techniques (PET, SPECT), lacks anatomical information, limiting the resolution of analyses of living systems. Furthermore, anatomical information from the subject under study can be used as a priori information for the FDOT reconstruction algorithm to improve its performance. With these goals in mind, we have built a proof-of-concept FDOT-CT hybrid machine that combines the high-resolution anatomy of CT with the functional information provided by FDOT.

Original languageEnglish (US)
Title of host publication2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
Pages5412-5413
Number of pages2
DOIs
StatePublished - Dec 1 2008
Externally publishedYes
Event2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 - Dresden, Germany
Duration: Oct 19 2008Oct 25 2008

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Other

Other2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008
CountryGermany
CityDresden
Period10/19/0810/25/08

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Aguirre, J., Sisniega, A., Ripoll, J., Desco, M., & Vaquero, J. J. (2008). Design and development of a co-planar fluorescence and X-ray tomograph. In 2008 IEEE Nuclear Science Symposium Conference Record, NSS/MIC 2008 (pp. 5412-5413). [4774456] (IEEE Nuclear Science Symposium Conference Record). https://doi.org/10.1109/NSSMIC.2008.4774456