Desferrioxamine ameliorates retinal photic injury in albino rats

Zi Liang Li, Sheridan Lam And, Mark O.M. Tso

Research output: Contribution to journalArticlepeer-review

Abstract

Albino rats were given intraperitoneal desferrioxamine before exposure to intense fluorescent light. Morphometric and morphologic studies of the retina indicated that there was better preservation of photoreceptor nuclei and fewer subretinal macrophages in rats treated with desferrioxamine than in the control rats. The results of the study imply that iron and hydroxyl radicals may be important mediators in photic retinal injury.

Original languageEnglish (US)
Pages (from-to)133-144
Number of pages12
JournalCurrent Eye Research
Volume10
Issue number2
DOIs
StatePublished - 1991
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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