Descrambling DSCAM Diversity

Rajnish Bharadwaj, Alex L. Kolodkin

Research output: Contribution to journalShort survey

Abstract

Neuronal processes exhibit exquisitely complex branching patterns crucial for the formation of distinct neural circuits. In this issue of Cell, Chen et al. (2006) show that the isoform diversity of the Dscam protein in Drosophila is required to establish stereotypical axonal branching patterns, suggesting that nonrandom expression of Dscam alternative splice variants determines neural connectivity.

Original languageEnglish (US)
Pages (from-to)421-424
Number of pages4
JournalCell
Volume125
Issue number3
DOIs
StatePublished - May 5 2006

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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