Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women

Ankita Prasad, Enrique F. Schisterman, Karen C. Schliep, Katherine A. Ahrens, Lindsey A. Sjaarda, Neil J. Perkins, Rebecca Matyas, Jean Wactawski-Wende, Sunni L. Mumford

Research output: Contribution to journalArticle

Abstract

Purpose: To determine whether depressive symptoms are associated with ovulation or reproductive hormone concentrations in eumenorrheic women without a reported diagnosis of clinical depression. Methods: A prospective cohort of 248 regularly menstruating women, aged 18 to 44years (27.3±8.2) were evaluated for depressive symptoms at baseline using the 20-item Center for Epidemiological Studies Depression (CES-D) scale and categorized dichotomously (.05) or the odds of sporadic anovulation (adjusted odds ratio, 1.1; 95% confidence interval, [0.02-5.0]), after adjusting for age, race, body mass index, perceived stress level, and alcohol consumption. Conclusions: Despite reported associations between mental health and menstrual cycle dysfunction, depressive symptoms were not associated with reproductive hormone concentrations or sporadic anovulation in this cohort of regularly menstruating women with no recent (within 1 year) self-reported history of clinical depression.

Original languageEnglish (US)
Pages (from-to)920-924
Number of pages5
JournalAnnals of Epidemiology
Volume24
Issue number12
DOIs
StatePublished - Dec 1 2014
Externally publishedYes

Fingerprint

Anovulation
Hormones
Depression
Mental Health Associations
Menstrual Cycle
Ovulation
Alcohol Drinking
Epidemiologic Studies
Body Mass Index
Odds Ratio
Confidence Intervals

Keywords

  • Depression
  • Depressive symptoms
  • Menstrual cycle
  • Mental health
  • Ovulation
  • Reproductive hormones
  • Women's health

ASJC Scopus subject areas

  • Epidemiology

Cite this

Prasad, A., Schisterman, E. F., Schliep, K. C., Ahrens, K. A., Sjaarda, L. A., Perkins, N. J., ... Mumford, S. L. (2014). Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women. Annals of Epidemiology, 24(12), 920-924. https://doi.org/10.1016/j.annepidem.2014.10.005

Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women. / Prasad, Ankita; Schisterman, Enrique F.; Schliep, Karen C.; Ahrens, Katherine A.; Sjaarda, Lindsey A.; Perkins, Neil J.; Matyas, Rebecca; Wactawski-Wende, Jean; Mumford, Sunni L.

In: Annals of Epidemiology, Vol. 24, No. 12, 01.12.2014, p. 920-924.

Research output: Contribution to journalArticle

Prasad, A, Schisterman, EF, Schliep, KC, Ahrens, KA, Sjaarda, LA, Perkins, NJ, Matyas, R, Wactawski-Wende, J & Mumford, SL 2014, 'Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women', Annals of Epidemiology, vol. 24, no. 12, pp. 920-924. https://doi.org/10.1016/j.annepidem.2014.10.005
Prasad, Ankita ; Schisterman, Enrique F. ; Schliep, Karen C. ; Ahrens, Katherine A. ; Sjaarda, Lindsey A. ; Perkins, Neil J. ; Matyas, Rebecca ; Wactawski-Wende, Jean ; Mumford, Sunni L. / Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women. In: Annals of Epidemiology. 2014 ; Vol. 24, No. 12. pp. 920-924.
@article{07eb36178a5d4f3aafa121b15f51a5b5,
title = "Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women",
abstract = "Purpose: To determine whether depressive symptoms are associated with ovulation or reproductive hormone concentrations in eumenorrheic women without a reported diagnosis of clinical depression. Methods: A prospective cohort of 248 regularly menstruating women, aged 18 to 44years (27.3±8.2) were evaluated for depressive symptoms at baseline using the 20-item Center for Epidemiological Studies Depression (CES-D) scale and categorized dichotomously (.05) or the odds of sporadic anovulation (adjusted odds ratio, 1.1; 95{\%} confidence interval, [0.02-5.0]), after adjusting for age, race, body mass index, perceived stress level, and alcohol consumption. Conclusions: Despite reported associations between mental health and menstrual cycle dysfunction, depressive symptoms were not associated with reproductive hormone concentrations or sporadic anovulation in this cohort of regularly menstruating women with no recent (within 1 year) self-reported history of clinical depression.",
keywords = "Depression, Depressive symptoms, Menstrual cycle, Mental health, Ovulation, Reproductive hormones, Women's health",
author = "Ankita Prasad and Schisterman, {Enrique F.} and Schliep, {Karen C.} and Ahrens, {Katherine A.} and Sjaarda, {Lindsey A.} and Perkins, {Neil J.} and Rebecca Matyas and Jean Wactawski-Wende and Mumford, {Sunni L.}",
year = "2014",
month = "12",
day = "1",
doi = "10.1016/j.annepidem.2014.10.005",
language = "English (US)",
volume = "24",
pages = "920--924",
journal = "Annals of Epidemiology",
issn = "1047-2797",
publisher = "Elsevier Inc.",
number = "12",

}

TY - JOUR

T1 - Depressive symptoms and their relationship with endogenous reproductive hormones and sporadic anovulation in premenopausal women

AU - Prasad, Ankita

AU - Schisterman, Enrique F.

AU - Schliep, Karen C.

AU - Ahrens, Katherine A.

AU - Sjaarda, Lindsey A.

AU - Perkins, Neil J.

AU - Matyas, Rebecca

AU - Wactawski-Wende, Jean

AU - Mumford, Sunni L.

PY - 2014/12/1

Y1 - 2014/12/1

N2 - Purpose: To determine whether depressive symptoms are associated with ovulation or reproductive hormone concentrations in eumenorrheic women without a reported diagnosis of clinical depression. Methods: A prospective cohort of 248 regularly menstruating women, aged 18 to 44years (27.3±8.2) were evaluated for depressive symptoms at baseline using the 20-item Center for Epidemiological Studies Depression (CES-D) scale and categorized dichotomously (.05) or the odds of sporadic anovulation (adjusted odds ratio, 1.1; 95% confidence interval, [0.02-5.0]), after adjusting for age, race, body mass index, perceived stress level, and alcohol consumption. Conclusions: Despite reported associations between mental health and menstrual cycle dysfunction, depressive symptoms were not associated with reproductive hormone concentrations or sporadic anovulation in this cohort of regularly menstruating women with no recent (within 1 year) self-reported history of clinical depression.

AB - Purpose: To determine whether depressive symptoms are associated with ovulation or reproductive hormone concentrations in eumenorrheic women without a reported diagnosis of clinical depression. Methods: A prospective cohort of 248 regularly menstruating women, aged 18 to 44years (27.3±8.2) were evaluated for depressive symptoms at baseline using the 20-item Center for Epidemiological Studies Depression (CES-D) scale and categorized dichotomously (.05) or the odds of sporadic anovulation (adjusted odds ratio, 1.1; 95% confidence interval, [0.02-5.0]), after adjusting for age, race, body mass index, perceived stress level, and alcohol consumption. Conclusions: Despite reported associations between mental health and menstrual cycle dysfunction, depressive symptoms were not associated with reproductive hormone concentrations or sporadic anovulation in this cohort of regularly menstruating women with no recent (within 1 year) self-reported history of clinical depression.

KW - Depression

KW - Depressive symptoms

KW - Menstrual cycle

KW - Mental health

KW - Ovulation

KW - Reproductive hormones

KW - Women's health

UR - http://www.scopus.com/inward/record.url?scp=84927178084&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84927178084&partnerID=8YFLogxK

U2 - 10.1016/j.annepidem.2014.10.005

DO - 10.1016/j.annepidem.2014.10.005

M3 - Article

C2 - 25453349

AN - SCOPUS:84927178084

VL - 24

SP - 920

EP - 924

JO - Annals of Epidemiology

JF - Annals of Epidemiology

SN - 1047-2797

IS - 12

ER -