Depressive symptomatology and hypertension-associated morbidity and mortality in older adults

Eleanor Marie Simonsick, Robert B. Wallace, Dan G. Blazer, Lisa F. Berkman

Research output: Contribution to journalArticle

Abstract

This study determines, in a population of older adults with diagnosed hypertension, the concurrent association between depressive symptomatology and blood pressure control and the longitudinal association between depressive symptomatology and blood pressure control, stroke, and cardiovascular-related mortality. Data are from the East Boston, Massachusetts; New Haven, Connecticut; and Iowa sites of the Established Populations for Epidemiologic Studies of the Elderly, conducted between 1982 and 1988. Age-adjusted site-and gender-specific analyses were conducted, unadjusted and adjusted for baseline health status. There was no consistent association, cross-sectionally or longitudinally, between depressive symptoms and blood pressure control. Rates of stroke were 2.3 to 2.7 times higher in most subgroups with high depressive symptomatology in contrast to their nondepressed counterparts. Rates of cardiovascular disease-related death were also elevated in most subgroups, achieving statistical significance in women from New Haven and Iowa. This study presents evidence that high depressive symptoms in older adults with diagnosed hypertension may place them at increased risk of stroke and possibly cardiovascular-related death relative to other elderly persons with diagnosed hypertension. Because the rate of stroke in this subpopulation was exceptionally high, further evaluation of the role of depressive symptoms in the progression of hypertensive disease seems warranted.

Original languageEnglish (US)
Pages (from-to)427-435
Number of pages9
JournalPsychosomatic Medicine
Volume57
Issue number5
StatePublished - 1995
Externally publishedYes

Fingerprint

Depression
Blood Pressure
Hypertension
Morbidity
Mortality
Stroke
Myocardial Infarction
Population
Health Status
Disease Progression
Epidemiologic Studies
Cardiovascular Diseases
Depressive Symptoms
New Haven
Cardiovascular Disease
Progression
Person
Evaluation

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Psychiatry and Mental health
  • Applied Psychology
  • Developmental and Educational Psychology
  • Psychology(all)

Cite this

Depressive symptomatology and hypertension-associated morbidity and mortality in older adults. / Simonsick, Eleanor Marie; Wallace, Robert B.; Blazer, Dan G.; Berkman, Lisa F.

In: Psychosomatic Medicine, Vol. 57, No. 5, 1995, p. 427-435.

Research output: Contribution to journalArticle

Simonsick, Eleanor Marie ; Wallace, Robert B. ; Blazer, Dan G. ; Berkman, Lisa F. / Depressive symptomatology and hypertension-associated morbidity and mortality in older adults. In: Psychosomatic Medicine. 1995 ; Vol. 57, No. 5. pp. 427-435.
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