Depolarization changes during ischemia detected through time-frequency analysis of the intracardiac electrogram

B. I. Gramatikov; I. Provaznik; N. V. Thakor

Depolarization changes during ischemia detected through time-frequency analysis of the intracardiac electrogram

B. I. Gramatikov, I. Provaznik, N. V. Thakor

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Epicardial and endocardial electrograms were recorded from isolated perfused rabbit hearts in which local ischemia was induced by occluding the LAD for short periods of time. Intracavitary and epicardial bipolar leads were found to be sensitive to ischemia in paced and non-paced beats. Both the intra-QRS electrogram and the ST level respond to ischemia whereas there are cases with the one showing differences with ischemia while the other is not. Intracardial leads can detect ischemia in a distal site. Hence the intra-QRS electrogram may be a valuable alternative to ST analysis in ischemia detection. This may find application in implantable devices.

Original language	English (US)
Pages (from-to)	289-292
Number of pages	4
Journal	Computers in cardiology
Volume	0
Issue number	0
State	Published - Dec 1 1998

ASJC Scopus subject areas

Computer Science Applications
Cardiology and Cardiovascular Medicine

Cite this

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AU - Provaznik, I.

AU - Thakor, N. V.

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N2 - Epicardial and endocardial electrograms were recorded from isolated perfused rabbit hearts in which local ischemia was induced by occluding the LAD for short periods of time. Intracavitary and epicardial bipolar leads were found to be sensitive to ischemia in paced and non-paced beats. Both the intra-QRS electrogram and the ST level respond to ischemia whereas there are cases with the one showing differences with ischemia while the other is not. Intracardial leads can detect ischemia in a distal site. Hence the intra-QRS electrogram may be a valuable alternative to ST analysis in ischemia detection. This may find application in implantable devices.

AB - Epicardial and endocardial electrograms were recorded from isolated perfused rabbit hearts in which local ischemia was induced by occluding the LAD for short periods of time. Intracavitary and epicardial bipolar leads were found to be sensitive to ischemia in paced and non-paced beats. Both the intra-QRS electrogram and the ST level respond to ischemia whereas there are cases with the one showing differences with ischemia while the other is not. Intracardial leads can detect ischemia in a distal site. Hence the intra-QRS electrogram may be a valuable alternative to ST analysis in ischemia detection. This may find application in implantable devices.

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Depolarization changes during ischemia detected through time-frequency analysis of the intracardiac electrogram

Abstract

ASJC Scopus subject areas

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