Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate): A potent selective 5-phosphatase inhibitor

Alan P. Kozikowski, Vassil I. Ognyanov, Chinpiao Chen, Abdul H. Fauq, Stephen T. Safrany, Robert A. Wilcox, Stefan R. Nahorski

Research output: Contribution to journalArticle

Original languageEnglish (US)
Pages (from-to)3035-3038
Number of pages4
JournalJournal of Medicinal Chemistry
Volume36
Issue number20
StatePublished - 1993
Externally publishedYes

Fingerprint

Cyclohexanes
Mesylates
Inositol 1,4,5-Trisphosphate
Phosphoprotein Phosphatases
Calcium Channels
Structure-Activity Relationship
Cytoplasmic and Nuclear Receptors
Molecular Structure
Phosphoric Monoester Hydrolases
Enzymes
cyclohexane-1,2,4-tris(methylenesulfonate)

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate) : A potent selective 5-phosphatase inhibitor. / Kozikowski, Alan P.; Ognyanov, Vassil I.; Chen, Chinpiao; Fauq, Abdul H.; Safrany, Stephen T.; Wilcox, Robert A.; Nahorski, Stefan R.

In: Journal of Medicinal Chemistry, Vol. 36, No. 20, 1993, p. 3035-3038.

Research output: Contribution to journalArticle

Kozikowski, Alan P. ; Ognyanov, Vassil I. ; Chen, Chinpiao ; Fauq, Abdul H. ; Safrany, Stephen T. ; Wilcox, Robert A. ; Nahorski, Stefan R. / Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate) : A potent selective 5-phosphatase inhibitor. In: Journal of Medicinal Chemistry. 1993 ; Vol. 36, No. 20. pp. 3035-3038.
@article{f8cf1248d1f84a748dba38be7d3ec70f,
title = "Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate): A potent selective 5-phosphatase inhibitor",
author = "Kozikowski, {Alan P.} and Ognyanov, {Vassil I.} and Chinpiao Chen and Fauq, {Abdul H.} and Safrany, {Stephen T.} and Wilcox, {Robert A.} and Nahorski, {Stefan R.}",
year = "1993",
language = "English (US)",
volume = "36",
pages = "3035--3038",
journal = "Journal of Medicinal Chemistry",
issn = "0022-2623",
publisher = "American Chemical Society",
number = "20",

}

TY - JOUR

T1 - Deoxygenated inositol 1,4,5-trisphosphate analogues and their interaction with metabolic enzymes. (1R,2R,4R)-cyclohexane-1,2,4-tris(methylenesulfonate)

T2 - A potent selective 5-phosphatase inhibitor

AU - Kozikowski, Alan P.

AU - Ognyanov, Vassil I.

AU - Chen, Chinpiao

AU - Fauq, Abdul H.

AU - Safrany, Stephen T.

AU - Wilcox, Robert A.

AU - Nahorski, Stefan R.

PY - 1993

Y1 - 1993

UR - http://www.scopus.com/inward/record.url?scp=0027362857&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027362857&partnerID=8YFLogxK

M3 - Article

C2 - 8411022

AN - SCOPUS:0027362857

VL - 36

SP - 3035

EP - 3038

JO - Journal of Medicinal Chemistry

JF - Journal of Medicinal Chemistry

SN - 0022-2623

IS - 20

ER -