Dengue Antibody and Zika: Friend or Foe?

Research output: Contribution to journalShort surveypeer-review

Abstract

Zika virus is a mosquito-borne Flavivirus related to dengue that is rapidly spreading through the Americas. This outbreak is occurring in dengue-endemic areas where the population has acquired antibodies to dengue. Recent studies reveal that preexisting dengue antibodies may have opposite effects on Zika infection, transmission, and clinical outcome. Discerning these effects is critical to a better understanding of Zika pathogenesis and the prevention of future outbreaks.

Original languageEnglish (US)
Pages (from-to)635-636
Number of pages2
JournalTrends in Immunology
Volume37
Issue number10
DOIs
StatePublished - Oct 1 2016

Keywords

  • Zika virus
  • antibody-dependent enhancement of infection
  • dengue virus

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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