Demonstration of an alcohol-chloroform insoluble, periodic acid-Schiff reactive substance in the hypothalamus of the rat

Theodore F. Leveque, Gerald A. Hofkin

Research output: Contribution to journalArticle

Abstract

An alcohol-chloroform insoluble, periodic acid-Schiff reactive substance associated with the ependymal lining of the supraoptic and infundibular recesses was demonstrated in the hypothalamus of the white rat. Although the ependyma is stratified and contains cells with long processes throughout the extent of the recesses, the PAS reactive substance is present in very circumscribed areas within the recesses. It was also shown that this PAS reactive substance is not related to neurosecretory material which has an affinity for chrome-alum hematoxylin and aldehyde fuchsin. The regularity of appearance and location of the substance may be taken as evidence in favor of its being a specific material elaborated in the regions mentioned. The possibility of the reactive material in each site representing different compounds, each of which is associated with a substance possessing 1,2-glycol groups, is discussed.

Original languageEnglish (US)
Pages (from-to)185-191
Number of pages7
JournalZeitschrift für Zellforschung und Mikroskopische Anatomie
Volume53
Issue number2
DOIs
StatePublished - Mar 1961
Externally publishedYes

Fingerprint

Ependyma
Rosaniline Dyes
Periodic Acid
Glycols
Chloroform
Aldehydes
Hypothalamus
Rats
Demonstrations
Alcohols
Linings
alum hematoxylin
chrome alum

ASJC Scopus subject areas

  • Anatomy
  • Clinical Biochemistry
  • Cell Biology
  • Medicine(all)

Cite this

Demonstration of an alcohol-chloroform insoluble, periodic acid-Schiff reactive substance in the hypothalamus of the rat. / Leveque, Theodore F.; Hofkin, Gerald A.

In: Zeitschrift für Zellforschung und Mikroskopische Anatomie, Vol. 53, No. 2, 03.1961, p. 185-191.

Research output: Contribution to journalArticle

@article{da4977b5aeb84cc69ed3808cdc221acb,
title = "Demonstration of an alcohol-chloroform insoluble, periodic acid-Schiff reactive substance in the hypothalamus of the rat",
abstract = "An alcohol-chloroform insoluble, periodic acid-Schiff reactive substance associated with the ependymal lining of the supraoptic and infundibular recesses was demonstrated in the hypothalamus of the white rat. Although the ependyma is stratified and contains cells with long processes throughout the extent of the recesses, the PAS reactive substance is present in very circumscribed areas within the recesses. It was also shown that this PAS reactive substance is not related to neurosecretory material which has an affinity for chrome-alum hematoxylin and aldehyde fuchsin. The regularity of appearance and location of the substance may be taken as evidence in favor of its being a specific material elaborated in the regions mentioned. The possibility of the reactive material in each site representing different compounds, each of which is associated with a substance possessing 1,2-glycol groups, is discussed.",
author = "Leveque, {Theodore F.} and Hofkin, {Gerald A.}",
year = "1961",
month = "3",
doi = "10.1007/BF00339441",
language = "English (US)",
volume = "53",
pages = "185--191",
journal = "Cell and Tissue Research",
issn = "0302-766X",
publisher = "Springer Verlag",
number = "2",

}

TY - JOUR

T1 - Demonstration of an alcohol-chloroform insoluble, periodic acid-Schiff reactive substance in the hypothalamus of the rat

AU - Leveque, Theodore F.

AU - Hofkin, Gerald A.

PY - 1961/3

Y1 - 1961/3

N2 - An alcohol-chloroform insoluble, periodic acid-Schiff reactive substance associated with the ependymal lining of the supraoptic and infundibular recesses was demonstrated in the hypothalamus of the white rat. Although the ependyma is stratified and contains cells with long processes throughout the extent of the recesses, the PAS reactive substance is present in very circumscribed areas within the recesses. It was also shown that this PAS reactive substance is not related to neurosecretory material which has an affinity for chrome-alum hematoxylin and aldehyde fuchsin. The regularity of appearance and location of the substance may be taken as evidence in favor of its being a specific material elaborated in the regions mentioned. The possibility of the reactive material in each site representing different compounds, each of which is associated with a substance possessing 1,2-glycol groups, is discussed.

AB - An alcohol-chloroform insoluble, periodic acid-Schiff reactive substance associated with the ependymal lining of the supraoptic and infundibular recesses was demonstrated in the hypothalamus of the white rat. Although the ependyma is stratified and contains cells with long processes throughout the extent of the recesses, the PAS reactive substance is present in very circumscribed areas within the recesses. It was also shown that this PAS reactive substance is not related to neurosecretory material which has an affinity for chrome-alum hematoxylin and aldehyde fuchsin. The regularity of appearance and location of the substance may be taken as evidence in favor of its being a specific material elaborated in the regions mentioned. The possibility of the reactive material in each site representing different compounds, each of which is associated with a substance possessing 1,2-glycol groups, is discussed.

UR - http://www.scopus.com/inward/record.url?scp=28944447567&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=28944447567&partnerID=8YFLogxK

U2 - 10.1007/BF00339441

DO - 10.1007/BF00339441

M3 - Article

C2 - 13761361

AN - SCOPUS:28944447567

VL - 53

SP - 185

EP - 191

JO - Cell and Tissue Research

JF - Cell and Tissue Research

SN - 0302-766X

IS - 2

ER -