TY - JOUR
T1 - Demonstration by synovial fluid analysis of the efficacy in horses of an investigational drug (L-1016)
AU - Tew, William P.
PY - 1982
Y1 - 1982
N2 - A glycosaminoglycan polysulfate ester, L-1016, was administered intra-articularly over a period of six-weeks to selected horses with joint disorders which demonstrated by synovial fluid analysis lesions and/or degeneration of the articular cartilage and impairment of synovial membrane function. Over the course of treatment, significant changes in synovial fluid viscosity and protein were observed. In general, these laboratory data were reflected directly in clinical observations. Response to the treatment was characterized by decreases in outward signs of swelling, increases in flexion and lessening of lameness.
AB - A glycosaminoglycan polysulfate ester, L-1016, was administered intra-articularly over a period of six-weeks to selected horses with joint disorders which demonstrated by synovial fluid analysis lesions and/or degeneration of the articular cartilage and impairment of synovial membrane function. Over the course of treatment, significant changes in synovial fluid viscosity and protein were observed. In general, these laboratory data were reflected directly in clinical observations. Response to the treatment was characterized by decreases in outward signs of swelling, increases in flexion and lessening of lameness.
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U2 - 10.1016/S0737-0806(82)80018-X
DO - 10.1016/S0737-0806(82)80018-X
M3 - Article
AN - SCOPUS:0346178186
SN - 0737-0806
VL - 2
SP - 42
EP - 50
JO - Journal of Equine Veterinary Science
JF - Journal of Equine Veterinary Science
IS - 2
ER -