Demons deformable registration for cone-beam CT guidance: Registration of pre- And intra-operative images

S. Nithiananthan, K. K. Brock, M. J. Daly, H. Chan, J. C. Irish, J. H. Siewerdsen

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

High-quality intraoperative 3D imaging systems such as cone-beam CT (CBCT) hold considerable promise for imageguided surgical procedures in the head and neck. With a large amount of preoperative imaging and planning information available in addition to the intraoperative images, it becomes desirable to be able to integrate all sources of imaging information within the same anatomical frame of reference using deformable image registration. Fast intensity-based algorithms are available which can perform deformable image registration within a period of time short enough for intraoperative use. However, CBCT images often contain voxel intensity inaccuracy which can hinder registration accuracy - for example, due to x-ray scatter, truncation, and/or erroneous scaling normalization within the 3D reconstruction algorithm. In this work, we present a method of integrating an iterative intensity matching step within the operation of a multi-scale Demons registration algorithm. Registration accuracy was evaluated in a cadaver model and showed that a conventional Demons implementation (with either no intensity match or a single histogram match) introduced anatomical distortion and degradation in target registration error (TRE). The iterative intensity matching procedure, on the other hand, provided robust registration across a broad range of intensity inaccuracies.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2010
Subtitle of host publicationVisualization, Image-Guided Procedures, and Modeling
EditorsKenneth H. Wong, Michael I. Miga
PublisherSPIE
ISBN (Electronic)9780819480262
DOIs
StatePublished - Jan 1 2010
EventMedical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling - San Diego, United States
Duration: Feb 14 2010Feb 16 2010

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7625
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2010: Visualization, Image-Guided Procedures, and Modeling
CountryUnited States
CitySan Diego
Period2/14/102/16/10

Keywords

  • 3D imaging
  • C-arm
  • Cone-beam CT
  • Flat-panel detector
  • Head and neck surgery
  • Image registration
  • Image-guided interventions
  • Surgical navigation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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