Demographic features and prevalence of idiopathic myocarditis in patients undergoing endomyocardial biopsy

Ahvie Herskowitz, Stephen Campbell, Jaap Deckers, Edward K Kasper, John Boehmer, Djavid Hadian, David A. Neumann, Kenneth L. Baughman

Research output: Contribution to journalArticle

Abstract

From January 1985 through December 1990, 534 patients underwent endomyocardial biopsy at Johns Hopkins Hospital for suspected myocarditis. One hundred thirty-eight (26%) biopsy specimens were diagnosed histologically by 2 cardiac pathologists as either active (n = 85, 16%) or borderline (n = 53, 10%) myocarditis. Of the 138 patients, 60 were excluded based on either specific concurrent clinical conditions or noncongestive heart failure presentations. Immunohistochemical staining for common leukocyte antigen infiltrating cells performed on the remaining 78 specimens confirmed the presence of focal or multifocal inflammatory infiltrates in 58, of which 49 had histologic evidence of active myocarditis. All 49 patients presented with congestive heart failure and left ventricular ejection fractions of

Original languageEnglish (US)
Pages (from-to)982-986
Number of pages5
JournalThe American Journal of Cardiology
Volume71
Issue number11
DOIs
StatePublished - Apr 15 1993

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Myocarditis
Demography
Biopsy
Heart Failure
CD45 Antigens
Stroke Volume
Staining and Labeling

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Demographic features and prevalence of idiopathic myocarditis in patients undergoing endomyocardial biopsy. / Herskowitz, Ahvie; Campbell, Stephen; Deckers, Jaap; Kasper, Edward K; Boehmer, John; Hadian, Djavid; Neumann, David A.; Baughman, Kenneth L.

In: The American Journal of Cardiology, Vol. 71, No. 11, 15.04.1993, p. 982-986.

Research output: Contribution to journalArticle

Herskowitz, A, Campbell, S, Deckers, J, Kasper, EK, Boehmer, J, Hadian, D, Neumann, DA & Baughman, KL 1993, 'Demographic features and prevalence of idiopathic myocarditis in patients undergoing endomyocardial biopsy', The American Journal of Cardiology, vol. 71, no. 11, pp. 982-986. https://doi.org/10.1016/0002-9149(93)90918-3
Herskowitz, Ahvie ; Campbell, Stephen ; Deckers, Jaap ; Kasper, Edward K ; Boehmer, John ; Hadian, Djavid ; Neumann, David A. ; Baughman, Kenneth L. / Demographic features and prevalence of idiopathic myocarditis in patients undergoing endomyocardial biopsy. In: The American Journal of Cardiology. 1993 ; Vol. 71, No. 11. pp. 982-986.
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