Demodicidosis in childhood acute lymphoblastic leukemia: An opportunistic infection occurring with immunosuppression

S. Percy Ivy, Crystal L. Mackall, Lia Gore, Ronald E. Gress, A. Howland Hartley

Research output: Contribution to journalArticle

Abstract

We report demodicidosis in 11 children with acute lymphoblastic leukemia and a mildly pruritic, erythematous papular dermatitis that developed in areas rich in sebaceous glands. Demodex eruptions were safely and effectively treated with 5% permethrin. Proliferation of commensal parasites of the skin, Demodex folliculorum and Demodex brevis may be an opportunistic infection of the skin in the immunocompromised host; the expected abrogation of cell-mediated immunity secondary to lymphocyte depletion predisposes some children given chemotherapy for leukemia to mite proliferation. (J PEDIATR 1995;127:751-4).

Original languageEnglish (US)
Pages (from-to)751-754
Number of pages4
JournalThe Journal of pediatrics
Volume127
Issue number5
DOIs
StatePublished - Nov 1995

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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