Delivery of synergistic polyphenol combinations using biopolymer-based systems: Advances in physicochemical properties, stability and bioavailability

Lan Zhang, David Julian McClements, Zhiliang Wei, Guoqing Wang, Xuebo Liu, Fuguo Liu

Research output: Contribution to journalArticle

Abstract

When consumed at sufficiently high levels, polyphenols may provide health benefits, which is linked to their antidiabetic, antiinflamatory, antimicrobial, antioxidant, antitumor, and hypolipidemic properties. Moreover, certain polyphenol combinations exhibit synergistic effects when delivered together - the combined polyphenols have a higher biological activity than the sum of the individual ones. However, the commercial application of polyphenols as nutraceuticals is currently limited because of their poor solubility characteristics; instability when exposed to light, heat, and alkaline conditions; and, low and inconsistent oral bioavailability. Colloidal delivery systems are being developed to overcome these challenges. In this article, we review the design, fabrication, and utilization of food-grade biopolymer-based delivery systems for the encapsulation of one or more polyphenols. In particular, we focus on the creation of delivery systems constructed from edible proteins and polysaccharides. The optimization of biopolymer-based delivery systems may lead to the development of innovative polyphenol-enriched functional foods that can improve human health and wellbeing.

Original languageEnglish (US)
Pages (from-to)2083-2097
Number of pages15
JournalCritical Reviews in Food Science and Nutrition
Volume60
Issue number12
DOIs
StatePublished - 2020

Keywords

  • Synergism
  • bioavailability
  • delivery systems
  • multiple polyphenols
  • protein-polysaccharide complexes

ASJC Scopus subject areas

  • Food Science
  • Industrial and Manufacturing Engineering

Fingerprint Dive into the research topics of 'Delivery of synergistic polyphenol combinations using biopolymer-based systems: Advances in physicochemical properties, stability and bioavailability'. Together they form a unique fingerprint.

  • Cite this