TY - JOUR
T1 - Delivery of synergistic polyphenol combinations using biopolymer-based systems
T2 - Advances in physicochemical properties, stability and bioavailability
AU - Zhang, Lan
AU - McClements, David Julian
AU - Wei, Zhiliang
AU - Wang, Guoqing
AU - Liu, Xuebo
AU - Liu, Fuguo
N1 - Funding Information:
This work was supported by The National Natural Science Foundation of China (No. 21808187), China Postdoctoral Science Foundation funded project (No. 2018M641027; No. 2019T120950), the Natural Science Foundation of Shaanxi Province (Grant No. 2018JQ3043), Chinese Universities Scientific Fund (Z109021714), Shaanxi Postdoctoral Science Foundation funded project (No. 2018BSHTDZZ21) and Young Talent Fund of University Association for Science and Technology in Shaanxi, China (Grant No. 20180202).
Publisher Copyright:
© 2019 Taylor & Francis Group, LLC.
PY - 2020/7/3
Y1 - 2020/7/3
N2 - When consumed at sufficiently high levels, polyphenols may provide health benefits, which is linked to their antidiabetic, antiinflamatory, antimicrobial, antioxidant, antitumor, and hypolipidemic properties. Moreover, certain polyphenol combinations exhibit synergistic effects when delivered together–the combined polyphenols have a higher biological activity than the sum of the individual ones. However, the commercial application of polyphenols as nutraceuticals is currently limited because of their poor solubility characteristics; instability when exposed to light, heat, and alkaline conditions; and, low and inconsistent oral bioavailability. Colloidal delivery systems are being developed to overcome these challenges. In this article, we review the design, fabrication, and utilization of food-grade biopolymer-based delivery systems for the encapsulation of one or more polyphenols. In particular, we focus on the creation of delivery systems constructed from edible proteins and polysaccharides. The optimization of biopolymer-based delivery systems may lead to the development of innovative polyphenol-enriched functional foods that can improve human health and wellbeing.
AB - When consumed at sufficiently high levels, polyphenols may provide health benefits, which is linked to their antidiabetic, antiinflamatory, antimicrobial, antioxidant, antitumor, and hypolipidemic properties. Moreover, certain polyphenol combinations exhibit synergistic effects when delivered together–the combined polyphenols have a higher biological activity than the sum of the individual ones. However, the commercial application of polyphenols as nutraceuticals is currently limited because of their poor solubility characteristics; instability when exposed to light, heat, and alkaline conditions; and, low and inconsistent oral bioavailability. Colloidal delivery systems are being developed to overcome these challenges. In this article, we review the design, fabrication, and utilization of food-grade biopolymer-based delivery systems for the encapsulation of one or more polyphenols. In particular, we focus on the creation of delivery systems constructed from edible proteins and polysaccharides. The optimization of biopolymer-based delivery systems may lead to the development of innovative polyphenol-enriched functional foods that can improve human health and wellbeing.
KW - Synergism
KW - bioavailability
KW - delivery systems
KW - multiple polyphenols
KW - protein-polysaccharide complexes
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U2 - 10.1080/10408398.2019.1630358
DO - 10.1080/10408398.2019.1630358
M3 - Review article
C2 - 31257900
AN - SCOPUS:85086523553
SN - 1040-8398
VL - 60
SP - 2083
EP - 2097
JO - Critical Reviews in Food Science and Nutrition
JF - Critical Reviews in Food Science and Nutrition
IS - 12
ER -