Abstract
Cosmetic injection of hyaluronic acid (HA) and other fillers is increasingly common, and the late complications of these relatively new procedures are now coming to medical attention. Three patients with delayed periocular swelling that began years after injection of HA are described, with CT, MRI, and histopathologic characterization. While HA fillers are marketed as having a temporary effect of several months, the authors demonstrate that they may persist in the body for up to 9 years. Unlike most previous reports, there was no inflammatory reaction or encapsulation, simply infiltration into more superficial subcutaneous layers. All cases improved after surgical biopsy and hyaluronidase injections. Delayed periocular swelling after filler injections from several years prior can mimic serious medical conditions. With a detailed history and high index of suspicion, one may avoid a costly and invasive workup.
| Original language | English (US) |
|---|---|
| Pages (from-to) | S116-S118 |
| Journal | Ophthalmic Plastic and Reconstructive Surgery |
| Volume | 33 |
| Issue number | 3S |
| DOIs | |
| State | Published - May 1 2017 |
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ASJC Scopus subject areas
- Surgery
- Ophthalmology
Cite this
Delayed Superficial Migration of Retained Hyaluronic Acid Years Following Periocular Injection. / Chang, Jessica R.; Baharestani, Samuel; Salek, Sherveen S.; Piluek, W. Jordan; Eberhart, Charles G; McCulley, Timothy J.
In: Ophthalmic Plastic and Reconstructive Surgery, Vol. 33, No. 3S, 01.05.2017, p. S116-S118.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Delayed Superficial Migration of Retained Hyaluronic Acid Years Following Periocular Injection
AU - Chang, Jessica R.
AU - Baharestani, Samuel
AU - Salek, Sherveen S.
AU - Piluek, W. Jordan
AU - Eberhart, Charles G
AU - McCulley, Timothy J
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Cosmetic injection of hyaluronic acid (HA) and other fillers is increasingly common, and the late complications of these relatively new procedures are now coming to medical attention. Three patients with delayed periocular swelling that began years after injection of HA are described, with CT, MRI, and histopathologic characterization. While HA fillers are marketed as having a temporary effect of several months, the authors demonstrate that they may persist in the body for up to 9 years. Unlike most previous reports, there was no inflammatory reaction or encapsulation, simply infiltration into more superficial subcutaneous layers. All cases improved after surgical biopsy and hyaluronidase injections. Delayed periocular swelling after filler injections from several years prior can mimic serious medical conditions. With a detailed history and high index of suspicion, one may avoid a costly and invasive workup.
AB - Cosmetic injection of hyaluronic acid (HA) and other fillers is increasingly common, and the late complications of these relatively new procedures are now coming to medical attention. Three patients with delayed periocular swelling that began years after injection of HA are described, with CT, MRI, and histopathologic characterization. While HA fillers are marketed as having a temporary effect of several months, the authors demonstrate that they may persist in the body for up to 9 years. Unlike most previous reports, there was no inflammatory reaction or encapsulation, simply infiltration into more superficial subcutaneous layers. All cases improved after surgical biopsy and hyaluronidase injections. Delayed periocular swelling after filler injections from several years prior can mimic serious medical conditions. With a detailed history and high index of suspicion, one may avoid a costly and invasive workup.
UR - http://www.scopus.com/inward/record.url?scp=85019934025&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019934025&partnerID=8YFLogxK
U2 - 10.1097/IOP.0000000000000434
DO - 10.1097/IOP.0000000000000434
M3 - Article
C2 - 25902386
AN - SCOPUS:85019934025
VL - 33
SP - S116-S118
JO - Ophthalmic Plastic and Reconstructive Surgery
JF - Ophthalmic Plastic and Reconstructive Surgery
SN - 0740-9303
IS - 3S
ER -