Delayed presentation of HIV among older individuals: a growing problem

Amy C. Justice, Matthew B. Goetz, Cameron N. Stewart, Brenna C. Hogan, Elizabeth Humes, Paula M. Luz, Jessica L. Castilho, Denis Nash, Ellen Brazier, Beverly Musick, Constantin Yiannoutsos, Karen Malateste, Antoine Jaquet, Morna Cornell, Tinei Shamu, Reena Rajasuriar, Awachana Jiamsakul, Keri N. Althoff

Research output: Contribution to journalReview articlepeer-review

Abstract

Late presentation for care is a major impediment to the prevention and effective treatment of HIV infection. Older individuals are at increased risk of late presentation, represent a growing proportion of people with late presentation, and might require interventions tailored to their age group. We provide a summary of the literature published globally between 2016–21 (reporting data from 1984–2018) and quantify the association of age with delayed presentation. Using the most common definitions of late presentation and older age from these earlier studies, we update this work with data from the International Epidemiology Databases to Evaluate AIDS (IeDEA) consortium, focusing on data from 2000–19, encompassing four continents. Finally, we consider how late presentation among older individuals might be more effectively addressed as electronic medical records become widely adopted.

Original languageEnglish (US)
Pages (from-to)e269-e280
JournalThe Lancet HIV
Volume9
Issue number4
DOIs
StatePublished - Apr 2022

ASJC Scopus subject areas

  • Infectious Diseases
  • Epidemiology
  • Virology
  • Immunology

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