TY - JOUR
T1 - Delayed graft function
T2 - Immediate and late impact
AU - Samaniego, Millie
AU - Baldwin, William M.
AU - Sanfilippo, Fred
PY - 1997
Y1 - 1997
N2 - Delayed graft function remains a frequent problem after renal transplanation, which is often associated with subsequent graft failure. The major risks for delayed graft function are incurred during organ procurement, preservation, and transplantation, and are predominated by ischemic injury. The cofactors associated with delayed graft function that lead to subsequent poor outcome include early acute rejection as well as immunologic risk factors for rejection, such as presensitization, human leukocyte antigen mismatch, and previous loss of graft. Numerous diagnostic and therapeutic approaches have been assessed in recent years, but predicting or modifying adverse outcomes associated with delayed graft function in a given patient remains unreliable.
AB - Delayed graft function remains a frequent problem after renal transplanation, which is often associated with subsequent graft failure. The major risks for delayed graft function are incurred during organ procurement, preservation, and transplantation, and are predominated by ischemic injury. The cofactors associated with delayed graft function that lead to subsequent poor outcome include early acute rejection as well as immunologic risk factors for rejection, such as presensitization, human leukocyte antigen mismatch, and previous loss of graft. Numerous diagnostic and therapeutic approaches have been assessed in recent years, but predicting or modifying adverse outcomes associated with delayed graft function in a given patient remains unreliable.
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M3 - Article
C2 - 9375266
AN - SCOPUS:0030787150
SN - 1062-4821
VL - 6
SP - 533
EP - 537
JO - Current Opinion in Nephrology and Hypertension
JF - Current Opinion in Nephrology and Hypertension
IS - 6
ER -