Definitive Diagnostic Evaluation of the Child With Arterial Ischemic Stroke and Approaches to Secondary Stroke Prevention

Sarah Lee; Prakash Muthusami; Bruce A. Wasserman; Jeremy J. Heit; Ronil V. Chandra; Ferdinand Hui; Matias Negrotto; Todd A. Abruzzo

doi:10.1097/RMR.0000000000000272

Definitive Diagnostic Evaluation of the Child With Arterial Ischemic Stroke and Approaches to Secondary Stroke Prevention

Sarah Lee, Prakash Muthusami, Bruce A. Wasserman, Jeremy J. Heit, Ronil V. Chandra, Ferdinand Hui, Matias Negrotto, Todd A. Abruzzo

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

In children with arterial ischemic stroke (AIS), the definitive diagnosis of stroke subtype and confirmation of stroke etiology is necessary to mitigate stroke morbidity and prevent recurrent stroke. The common causes of AIS in children are sharply differentiated from the common causes of adult AIS. A comprehensive, structured diagnostic approach will identify the etiology of stroke in most children. Adequate diagnostic evaluation relies on advanced brain imaging and vascular imaging studies. A variety of medical and surgical secondary stroke prevention strategies directed at the underlying cause of stroke are available. This review aims to outline strategies for definitive diagnosis and secondary stroke prevention in children with AIS, emphasizing the critical role of neuroimaging.

Original language	English (US)
Pages (from-to)	225-230
Number of pages	6
Journal	Topics in Magnetic Resonance Imaging
Volume	30
Issue number	5
DOIs	https://doi.org/10.1097/RMR.0000000000000272
State	Published - Oct 1 2021

Keywords

pediatric neuroimaging
pediatric stroke
secondary stroke prevention
stroke diagnosis

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1097/RMR.0000000000000272

Cite this

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title = "Definitive Diagnostic Evaluation of the Child With Arterial Ischemic Stroke and Approaches to Secondary Stroke Prevention",

abstract = "In children with arterial ischemic stroke (AIS), the definitive diagnosis of stroke subtype and confirmation of stroke etiology is necessary to mitigate stroke morbidity and prevent recurrent stroke. The common causes of AIS in children are sharply differentiated from the common causes of adult AIS. A comprehensive, structured diagnostic approach will identify the etiology of stroke in most children. Adequate diagnostic evaluation relies on advanced brain imaging and vascular imaging studies. A variety of medical and surgical secondary stroke prevention strategies directed at the underlying cause of stroke are available. This review aims to outline strategies for definitive diagnosis and secondary stroke prevention in children with AIS, emphasizing the critical role of neuroimaging.",

keywords = "pediatric neuroimaging, pediatric stroke, secondary stroke prevention, stroke diagnosis",

author = "Sarah Lee and Prakash Muthusami and Wasserman, {Bruce A.} and Heit, {Jeremy J.} and Chandra, {Ronil V.} and Ferdinand Hui and Matias Negrotto and Abruzzo, {Todd A.}",

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T1 - Definitive Diagnostic Evaluation of the Child With Arterial Ischemic Stroke and Approaches to Secondary Stroke Prevention

AU - Lee, Sarah

AU - Muthusami, Prakash

AU - Wasserman, Bruce A.

AU - Heit, Jeremy J.

AU - Chandra, Ronil V.

AU - Hui, Ferdinand

AU - Negrotto, Matias

AU - Abruzzo, Todd A.

PY - 2021/10/1

Y1 - 2021/10/1

N2 - In children with arterial ischemic stroke (AIS), the definitive diagnosis of stroke subtype and confirmation of stroke etiology is necessary to mitigate stroke morbidity and prevent recurrent stroke. The common causes of AIS in children are sharply differentiated from the common causes of adult AIS. A comprehensive, structured diagnostic approach will identify the etiology of stroke in most children. Adequate diagnostic evaluation relies on advanced brain imaging and vascular imaging studies. A variety of medical and surgical secondary stroke prevention strategies directed at the underlying cause of stroke are available. This review aims to outline strategies for definitive diagnosis and secondary stroke prevention in children with AIS, emphasizing the critical role of neuroimaging.

AB - In children with arterial ischemic stroke (AIS), the definitive diagnosis of stroke subtype and confirmation of stroke etiology is necessary to mitigate stroke morbidity and prevent recurrent stroke. The common causes of AIS in children are sharply differentiated from the common causes of adult AIS. A comprehensive, structured diagnostic approach will identify the etiology of stroke in most children. Adequate diagnostic evaluation relies on advanced brain imaging and vascular imaging studies. A variety of medical and surgical secondary stroke prevention strategies directed at the underlying cause of stroke are available. This review aims to outline strategies for definitive diagnosis and secondary stroke prevention in children with AIS, emphasizing the critical role of neuroimaging.

KW - pediatric neuroimaging

KW - pediatric stroke

KW - secondary stroke prevention

KW - stroke diagnosis

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SN - 0899-3459

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Definitive Diagnostic Evaluation of the Child With Arterial Ischemic Stroke and Approaches to Secondary Stroke Prevention

Abstract

Keywords

ASJC Scopus subject areas

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