Definitions and validation criteria for biomarkers and surrogate endpoints: Development and testing of a quantitative hierarchical levels of evidence schema

Marissa N. Lassere, Kent R. Johnson, Maarten Boers, Peter Tugwell, Peter Brooks, Lee Simon, Vibeke Strand, Philip G. Conaghan, Mikkel Østergaard, Walter P. Maksymowych, Robert Landewé, Barry Bresnihan, Paul Peter Tak, Richard Wakefield, Philip Mease, Clifton O. Bingham, Michael Hughes, Doug Altman, Marc Buyse, Sally GalbraithGeorge Wells

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Medicine & Life Sciences