Defining the Role of Astrocytes in Neuromodulation

Nicolas X. Tritsch, Dwight E. Bergles

Research output: Contribution to journalShort surveypeer-review

Abstract

Astrocytes undergo elevations in intracellular calcium following activation of metabotropic receptors, which may trigger glutamate secretion and excitation of surrounding neurons. In this issue of Neuron, Fiacco et al. use transgenic mice that express a foreign Gq-coupled receptor in astrocytes to show that selective stimulation of astrocytes is not sufficient to induce the release of glutamate.

Original languageEnglish (US)
Pages (from-to)497-500
Number of pages4
JournalNeuron
Volume54
Issue number4
DOIs
StatePublished - May 24 2007

ASJC Scopus subject areas

  • Neuroscience(all)

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