Defining and interpreting pregnancy success rates for in vitro fertilization

L. S. Wilcox, H. B. Peterson, F. P. Haseltine, M. C. Martin

Research output: Contribution to journalArticle

Abstract

Objectives: To review current practice in describing pregnancy success rates after IVF-ET, to identify issues associated with interpreting these rates, and to suggest useful methods of describing these rates in the future. Design: Review of literature concerning medical, epidemiologic, and statistical aspects of reporting IVF-ET pregnancy success rates. Setting: The United States. Patients: Infertile couples participating in IVF-ET. Main Outcome Measures: Usefulness and accuracy of IVF-ET pregnancy reporting. Results: Several groups have collected information on the pregnancy success rates of IVF-ET clinics and have discussed appropriate definitions of pregnancy success. The largest of these groups in the United States is The American Fertility Society and its affiliate, the Society for Assisted Reproductive Technology. The number of live deliveries per 100 ET procedures and the number of live deliveries per 100 egg retrieval procedures are among the most commonly used definitions. Conclusion: The most commonly used definitions are particularly useful for describing the probability that a live infant will be delivered after IVF-ET is completed. To measure the effectiveness of the IVF-ET procedures and the costs of undergoing IVF-ET, other definitions are also important. Success rates need to be stratified by patient characteristics, such as age, that affect the probability of success.

Original languageEnglish (US)
Pages (from-to)18-25
Number of pages8
JournalFertility and Sterility
Volume60
Issue number1
StatePublished - 1993
Externally publishedYes

Fingerprint

Pregnancy Rate
Fertilization in Vitro
Pregnancy
Assisted Reproductive Techniques
Ovum
Fertility
Outcome Assessment (Health Care)
Costs and Cost Analysis

Keywords

  • In vitro fertilization
  • pregnancy
  • statistics

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Wilcox, L. S., Peterson, H. B., Haseltine, F. P., & Martin, M. C. (1993). Defining and interpreting pregnancy success rates for in vitro fertilization. Fertility and Sterility, 60(1), 18-25.

Defining and interpreting pregnancy success rates for in vitro fertilization. / Wilcox, L. S.; Peterson, H. B.; Haseltine, F. P.; Martin, M. C.

In: Fertility and Sterility, Vol. 60, No. 1, 1993, p. 18-25.

Research output: Contribution to journalArticle

Wilcox, LS, Peterson, HB, Haseltine, FP & Martin, MC 1993, 'Defining and interpreting pregnancy success rates for in vitro fertilization', Fertility and Sterility, vol. 60, no. 1, pp. 18-25.
Wilcox LS, Peterson HB, Haseltine FP, Martin MC. Defining and interpreting pregnancy success rates for in vitro fertilization. Fertility and Sterility. 1993;60(1):18-25.
Wilcox, L. S. ; Peterson, H. B. ; Haseltine, F. P. ; Martin, M. C. / Defining and interpreting pregnancy success rates for in vitro fertilization. In: Fertility and Sterility. 1993 ; Vol. 60, No. 1. pp. 18-25.
@article{f2a15b86092e45568ea0bbd6862d1f1b,
title = "Defining and interpreting pregnancy success rates for in vitro fertilization",
abstract = "Objectives: To review current practice in describing pregnancy success rates after IVF-ET, to identify issues associated with interpreting these rates, and to suggest useful methods of describing these rates in the future. Design: Review of literature concerning medical, epidemiologic, and statistical aspects of reporting IVF-ET pregnancy success rates. Setting: The United States. Patients: Infertile couples participating in IVF-ET. Main Outcome Measures: Usefulness and accuracy of IVF-ET pregnancy reporting. Results: Several groups have collected information on the pregnancy success rates of IVF-ET clinics and have discussed appropriate definitions of pregnancy success. The largest of these groups in the United States is The American Fertility Society and its affiliate, the Society for Assisted Reproductive Technology. The number of live deliveries per 100 ET procedures and the number of live deliveries per 100 egg retrieval procedures are among the most commonly used definitions. Conclusion: The most commonly used definitions are particularly useful for describing the probability that a live infant will be delivered after IVF-ET is completed. To measure the effectiveness of the IVF-ET procedures and the costs of undergoing IVF-ET, other definitions are also important. Success rates need to be stratified by patient characteristics, such as age, that affect the probability of success.",
keywords = "In vitro fertilization, pregnancy, statistics",
author = "Wilcox, {L. S.} and Peterson, {H. B.} and Haseltine, {F. P.} and Martin, {M. C.}",
year = "1993",
language = "English (US)",
volume = "60",
pages = "18--25",
journal = "Fertility and Sterility",
issn = "0015-0282",
publisher = "Elsevier Inc.",
number = "1",

}

TY - JOUR

T1 - Defining and interpreting pregnancy success rates for in vitro fertilization

AU - Wilcox, L. S.

AU - Peterson, H. B.

AU - Haseltine, F. P.

AU - Martin, M. C.

PY - 1993

Y1 - 1993

N2 - Objectives: To review current practice in describing pregnancy success rates after IVF-ET, to identify issues associated with interpreting these rates, and to suggest useful methods of describing these rates in the future. Design: Review of literature concerning medical, epidemiologic, and statistical aspects of reporting IVF-ET pregnancy success rates. Setting: The United States. Patients: Infertile couples participating in IVF-ET. Main Outcome Measures: Usefulness and accuracy of IVF-ET pregnancy reporting. Results: Several groups have collected information on the pregnancy success rates of IVF-ET clinics and have discussed appropriate definitions of pregnancy success. The largest of these groups in the United States is The American Fertility Society and its affiliate, the Society for Assisted Reproductive Technology. The number of live deliveries per 100 ET procedures and the number of live deliveries per 100 egg retrieval procedures are among the most commonly used definitions. Conclusion: The most commonly used definitions are particularly useful for describing the probability that a live infant will be delivered after IVF-ET is completed. To measure the effectiveness of the IVF-ET procedures and the costs of undergoing IVF-ET, other definitions are also important. Success rates need to be stratified by patient characteristics, such as age, that affect the probability of success.

AB - Objectives: To review current practice in describing pregnancy success rates after IVF-ET, to identify issues associated with interpreting these rates, and to suggest useful methods of describing these rates in the future. Design: Review of literature concerning medical, epidemiologic, and statistical aspects of reporting IVF-ET pregnancy success rates. Setting: The United States. Patients: Infertile couples participating in IVF-ET. Main Outcome Measures: Usefulness and accuracy of IVF-ET pregnancy reporting. Results: Several groups have collected information on the pregnancy success rates of IVF-ET clinics and have discussed appropriate definitions of pregnancy success. The largest of these groups in the United States is The American Fertility Society and its affiliate, the Society for Assisted Reproductive Technology. The number of live deliveries per 100 ET procedures and the number of live deliveries per 100 egg retrieval procedures are among the most commonly used definitions. Conclusion: The most commonly used definitions are particularly useful for describing the probability that a live infant will be delivered after IVF-ET is completed. To measure the effectiveness of the IVF-ET procedures and the costs of undergoing IVF-ET, other definitions are also important. Success rates need to be stratified by patient characteristics, such as age, that affect the probability of success.

KW - In vitro fertilization

KW - pregnancy

KW - statistics

UR - http://www.scopus.com/inward/record.url?scp=0027175834&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027175834&partnerID=8YFLogxK

M3 - Article

C2 - 8513941

AN - SCOPUS:0027175834

VL - 60

SP - 18

EP - 25

JO - Fertility and Sterility

JF - Fertility and Sterility

SN - 0015-0282

IS - 1

ER -