Defective suppressor cell generation in juvenile onset diabetes

M. M. Lederman, J. J. Ellner, H. M. Rodman

Research output: Contribution to journalArticle

Abstract

Lymphocytes of juvenile onset, insulin-dependent diabetics failed to generate suppressor cell activity after preincubation with concanavalin A (Con A). The mean suppression of the autologous proliferative response to phytohemagglutinin (PHA) was 6.1 ± 7.8% (mean ± SEM) in the diabetics and 34.0 ± 4.9% in 9 age-matched healthy controls (p

Original languageEnglish (US)
Pages (from-to)2051-2055
Number of pages5
JournalJournal of Immunology
Volume127
Issue number5
StatePublished - 1981
Externally publishedYes

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Phytohemagglutinins
Concanavalin A
Type 1 Diabetes Mellitus
Lymphocytes
Insulin

ASJC Scopus subject areas

  • Immunology

Cite this

Lederman, M. M., Ellner, J. J., & Rodman, H. M. (1981). Defective suppressor cell generation in juvenile onset diabetes. Journal of Immunology, 127(5), 2051-2055.

Defective suppressor cell generation in juvenile onset diabetes. / Lederman, M. M.; Ellner, J. J.; Rodman, H. M.

In: Journal of Immunology, Vol. 127, No. 5, 1981, p. 2051-2055.

Research output: Contribution to journalArticle

Lederman, MM, Ellner, JJ & Rodman, HM 1981, 'Defective suppressor cell generation in juvenile onset diabetes', Journal of Immunology, vol. 127, no. 5, pp. 2051-2055.
Lederman MM, Ellner JJ, Rodman HM. Defective suppressor cell generation in juvenile onset diabetes. Journal of Immunology. 1981;127(5):2051-2055.
Lederman, M. M. ; Ellner, J. J. ; Rodman, H. M. / Defective suppressor cell generation in juvenile onset diabetes. In: Journal of Immunology. 1981 ; Vol. 127, No. 5. pp. 2051-2055.
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