Decreased interleukin-1 and interleukin-2 production after splenectomy

Z. Spirer; R. Arav-Boger; V. Zakuth; E. Tzehoval; S. Dagan; B. Lev; A. Golander; I. Melamed

Decreased interleukin-1 and interleukin-2 production after splenectomy

Z. Spirer, R. Arav-Boger, V. Zakuth, E. Tzehoval, S. Dagan, B. Lev, A. Golander, I. Melamed

Research output: Contribution to journal › Article › peer-review

Abstract

Production of interleukin-1 and of interleukin-2 was measured in 57 splenectomized patients. 11 of them were after elective operations (aged 14-37 years, mean 24) and 46 posttraumatic (aged 20-36, mean 23) and in 20 appropriate controls. There was significant reduction of both interleukins in the splenectomized group, more evident in the elective group. The deficiency was not related to age of patient or time since splenectomy. These results support the view that a consequence of splenectomy is immunoregulatory deficit.

Original language	English (US)
Pages (from-to)	374-377, 426
Journal	Harefuah
Volume	126
Issue number	7
State	Published - Apr 1 1994
Externally published	Yes

ASJC Scopus subject areas

General Medicine

Cite this

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title = "Decreased interleukin-1 and interleukin-2 production after splenectomy",

abstract = "Production of interleukin-1 and of interleukin-2 was measured in 57 splenectomized patients. 11 of them were after elective operations (aged 14-37 years, mean 24) and 46 posttraumatic (aged 20-36, mean 23) and in 20 appropriate controls. There was significant reduction of both interleukins in the splenectomized group, more evident in the elective group. The deficiency was not related to age of patient or time since splenectomy. These results support the view that a consequence of splenectomy is immunoregulatory deficit.",

author = "Z. Spirer and R. Arav-Boger and V. Zakuth and E. Tzehoval and S. Dagan and B. Lev and A. Golander and I. Melamed",

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language = "English (US)",

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pages = "374--377, 426",

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T1 - Decreased interleukin-1 and interleukin-2 production after splenectomy

AU - Spirer, Z.

AU - Arav-Boger, R.

AU - Zakuth, V.

AU - Tzehoval, E.

AU - Dagan, S.

AU - Lev, B.

AU - Golander, A.

AU - Melamed, I.

PY - 1994/4/1

Y1 - 1994/4/1

N2 - Production of interleukin-1 and of interleukin-2 was measured in 57 splenectomized patients. 11 of them were after elective operations (aged 14-37 years, mean 24) and 46 posttraumatic (aged 20-36, mean 23) and in 20 appropriate controls. There was significant reduction of both interleukins in the splenectomized group, more evident in the elective group. The deficiency was not related to age of patient or time since splenectomy. These results support the view that a consequence of splenectomy is immunoregulatory deficit.

AB - Production of interleukin-1 and of interleukin-2 was measured in 57 splenectomized patients. 11 of them were after elective operations (aged 14-37 years, mean 24) and 46 posttraumatic (aged 20-36, mean 23) and in 20 appropriate controls. There was significant reduction of both interleukins in the splenectomized group, more evident in the elective group. The deficiency was not related to age of patient or time since splenectomy. These results support the view that a consequence of splenectomy is immunoregulatory deficit.

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M3 - Article

C2 - 8200582

AN - SCOPUS:0028411285

SN - 0017-7768

VL - 126

SP - 374-377, 426

JO - Harefuah

JF - Harefuah

IS - 7

ER -

Decreased interleukin-1 and interleukin-2 production after splenectomy

Abstract

ASJC Scopus subject areas

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