Decreased induction morbidity and mortality following modification to induction therapy in infants with acute lymphoblastic leukemia enrolled on AALL0631: A report from the children's oncology group

Wanda L. Salzer, Tamekia L. Jones, Meenakshi Devidas, Zoann E. Dreyer, Lia Gore, Naomi J. Winick, Lillian Sung, Elizabeth Raetz, Mignon L. Loh, Cindy Y. Wang, Paola De Lorenzo, Maria Grazia Valsecchi, Rob Pieters, William L. Carroll, Stephen P. Hunger, Joanne M. Hilden, Patrick A Brown

Research output: Contribution to journalArticle

Abstract

Background: Infants with acute lymphoblastic leukemia (ALL) have a poor prognosis. Intensification of therapy has resulted in fewer relapses but increased early deaths, resulting in failure to improve survival. Procedure: AALL0631 is a Phase 3 study for infants (

Original languageEnglish (US)
Pages (from-to)414-418
Number of pages5
JournalPediatric Blood and Cancer
Volume62
Issue number3
DOIs
StatePublished - Mar 1 2015

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Keywords

  • Infant acute lymphoblastic leukemia
  • Mortality

ASJC Scopus subject areas

  • Oncology
  • Pediatrics, Perinatology, and Child Health
  • Hematology

Cite this

Salzer, W. L., Jones, T. L., Devidas, M., Dreyer, Z. E., Gore, L., Winick, N. J., Sung, L., Raetz, E., Loh, M. L., Wang, C. Y., De Lorenzo, P., Valsecchi, M. G., Pieters, R., Carroll, W. L., Hunger, S. P., Hilden, J. M., & Brown, P. A. (2015). Decreased induction morbidity and mortality following modification to induction therapy in infants with acute lymphoblastic leukemia enrolled on AALL0631: A report from the children's oncology group. Pediatric Blood and Cancer, 62(3), 414-418. https://doi.org/10.1002/pbc.25311