TY - JOUR
T1 - Decreased cognitive function in aging non-insulin-dependent diabetic patients
AU - Perlmuter, Lawrence C.
AU - Hakami, Malekeh K.
AU - Hodgson-Harrington, Catherine
AU - Ginsberg, Jay
AU - Katz, Joanne
AU - Singer, Daniel E.
AU - Nathan, David M.
N1 - Funding Information:
Clinic, the Department of Oral Biology and Pathophysiology, Harvard School of Dental Medicine, the Diabetes Unit, Medical Practices Evaluation Unit and Medical Services, Massachusetts General Hospital, and the Department of Medicine, Harvard Medical School, Boston, Massachusetts. This work was supported in part by Grant AG-02300 from the United States Public Health Service, National Institutes on Aging, and was presented in part at the American Diabetes Association Meeting, San Antonio, Texas, 1983. Dr. Singer is a Henry J. Kaiser Family Foundation Faculty Scholar in General Internal Medicine. Requests for reprints should be addressed to Dr. Lawrence C. Perlmuter, Memory and Learning Clinic, Veterans Outpatient Clinic, 17 Court Street, Boston, Massachusetts 02108. Manuscript accepted June 14, 1984.
PY - 1984/12
Y1 - 1984/12
N2 - A cross-sectional study was conducted to determine whether normal, age-related declines in cognitive function are accelerated in non-insulin-dependent (type II) diabetes mellitus. Study participants ranged in age from 55 to 74 years. Results indicate that cognitive function is inferior in the patients with type II diabetes compared with a comparably aged, nondiabetic control group. On the basis of a series of cognitive tests, it appears that the cognitive impairment is due to a deficiency in memory retrieval rather than to an attentional or encoding deficit. Cognitive performance is poorer in diabetic patients with peripheral neuropathy or elevated hemoglobin A1c levels. The apparent cognitive impairment in aging patients with type II diabetes may complicate adherence to medical regimens.
AB - A cross-sectional study was conducted to determine whether normal, age-related declines in cognitive function are accelerated in non-insulin-dependent (type II) diabetes mellitus. Study participants ranged in age from 55 to 74 years. Results indicate that cognitive function is inferior in the patients with type II diabetes compared with a comparably aged, nondiabetic control group. On the basis of a series of cognitive tests, it appears that the cognitive impairment is due to a deficiency in memory retrieval rather than to an attentional or encoding deficit. Cognitive performance is poorer in diabetic patients with peripheral neuropathy or elevated hemoglobin A1c levels. The apparent cognitive impairment in aging patients with type II diabetes may complicate adherence to medical regimens.
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U2 - 10.1016/0002-9343(84)90186-4
DO - 10.1016/0002-9343(84)90186-4
M3 - Article
C2 - 6334441
AN - SCOPUS:0021682933
SN - 0002-9343
VL - 77
SP - 1043
EP - 1048
JO - The American journal of medicine
JF - The American journal of medicine
IS - 6
ER -