Decrease in shigellosis-related deaths without shigella spp.- specific interventions, Asia

Pradip Bardhan, A. S.G. Faruque, Aliya Naheed, David A. Sack

Research output: Contribution to journalArticlepeer-review

Abstract

In 1999, a review of the literature for 1966-1997 suggested that ≈1.1 million persons die annually of shigellosis, including ≈880,000 in Asia. Our recent review of the literature for 1990-2009 indicates that ≈125 million shigellosis cases occur annually in Asia, of which ≈14,000 are fatal. This estimate for illnesses is similar to the earlier estimate, but the number of deaths is 98% lower; that is, the lower estimate of deaths is associated with markedly reduced case fatality rates rather than fewer cases. Shigella spp.-related deaths decreased substantially during a period without Shigella spp.-specific interventions. We speculate that non specific interventions, e.g., measles vaccination, vitamin A supplementation, and improved nutrition, may have led to the reduced number of shigellosis-related deaths.

Original languageEnglish (US)
Pages (from-to)1718-1723
Number of pages6
JournalEmerging infectious diseases
Volume16
Issue number11
DOIs
StatePublished - Oct 2010

ASJC Scopus subject areas

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

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