TY - JOUR
T1 - Decoding the superior parietal lobule connections of the superior longitudinal fasciculus/arcuate fasciculus in the human brain
AU - Kamali, A.
AU - Sair, H. I.
AU - Radmanesh, A.
AU - Hasan, K. M.
N1 - Funding Information:
This work is funded by the American National Institutes of Health (NIH)-Institute for Neurological Diseases and Stroke ( NIH-NINDS : R01-NS052505-04 ) and the Dunn Research Foundation . The purchase of the 3.0-T MRI clinical scanner was partially funded by NIH grant S10 RR19186 awarded to Dr. Ponnada A. Narayana. We wish to thank Vipul Kumar Patel for helping in data acquisition.
PY - 2014/9/26
Y1 - 2014/9/26
N2 - The temporo-parietal (TP) white matter connections between the inferior parietal lobule and superior temporal gyrus as part of the superior longitudinal fasciculus/arcuate fasciculus (SLF/AF) or middle longitudinal fasciculus (MdLF) have been studied in prior diffusion tensor tractography (DTT) studies. However, few studies have been focusing on the higher TP connections of the superior parietal lobule with the temporal lobe. These higher TP connections have been shown to have a role in core processes such as attention, memory, emotions, and language. Our most recent study, for the first time, hinted to the possibility of a long white matter connection interconnecting the superior parietal lobule (SPL) with the posterior temporal lobe in human brain which we call the SLF/AF TP-SPL and for a shorter abbreviation, the TP-SPL. We decided to further investigate this white matter connection using fiber assignment by continuous tracking deterministic tractography and high spatial resolution diffusion tensor imaging on 3T. Five healthy right-handed men (age range 24-37. years) were studied. We delineated the SPL connections of the SLF/AF TP bilaterally in five normal adult human brains. Using a high resolution DTT technique, we demonstrate for the first time, the trajectory of a long fiber bundle connectivity between the SPL and posterior temporal lobe, called the SLF/AF TP-SPL (or the TP-SPL), bilaterally in five healthy adult human brains. We also demonstrate the trajectory of the vertically oriented posterior TP connections, interconnecting the inferior parietal lobule (IPL) with the posterior temporal lobe (TP-IPL) in relation to the TP-SPL, arcuate fasciculus and other major language pathways. In the current study, for the first time, we categorized the TP connections into the anterior and posterior connectivity groups and subcategorized each one into the SPL or IPL connections.
AB - The temporo-parietal (TP) white matter connections between the inferior parietal lobule and superior temporal gyrus as part of the superior longitudinal fasciculus/arcuate fasciculus (SLF/AF) or middle longitudinal fasciculus (MdLF) have been studied in prior diffusion tensor tractography (DTT) studies. However, few studies have been focusing on the higher TP connections of the superior parietal lobule with the temporal lobe. These higher TP connections have been shown to have a role in core processes such as attention, memory, emotions, and language. Our most recent study, for the first time, hinted to the possibility of a long white matter connection interconnecting the superior parietal lobule (SPL) with the posterior temporal lobe in human brain which we call the SLF/AF TP-SPL and for a shorter abbreviation, the TP-SPL. We decided to further investigate this white matter connection using fiber assignment by continuous tracking deterministic tractography and high spatial resolution diffusion tensor imaging on 3T. Five healthy right-handed men (age range 24-37. years) were studied. We delineated the SPL connections of the SLF/AF TP bilaterally in five normal adult human brains. Using a high resolution DTT technique, we demonstrate for the first time, the trajectory of a long fiber bundle connectivity between the SPL and posterior temporal lobe, called the SLF/AF TP-SPL (or the TP-SPL), bilaterally in five healthy adult human brains. We also demonstrate the trajectory of the vertically oriented posterior TP connections, interconnecting the inferior parietal lobule (IPL) with the posterior temporal lobe (TP-IPL) in relation to the TP-SPL, arcuate fasciculus and other major language pathways. In the current study, for the first time, we categorized the TP connections into the anterior and posterior connectivity groups and subcategorized each one into the SPL or IPL connections.
KW - Arcuate fasciculus
KW - Inferior parietal lobule
KW - Language pathways
KW - Superior parietal lobule
KW - Temporoparietal
KW - Tractography
UR - http://www.scopus.com/inward/record.url?scp=84907024960&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84907024960&partnerID=8YFLogxK
U2 - 10.1016/j.neuroscience.2014.07.035
DO - 10.1016/j.neuroscience.2014.07.035
M3 - Article
C2 - 25086308
AN - SCOPUS:84907024960
VL - 277
SP - 577
EP - 583
JO - Neuroscience
JF - Neuroscience
SN - 0306-4522
ER -