Decoding of MSTd population activity accounts for variations in the precision of heading perception

Yong Gu, Christopher R. Fetsch, Babatunde Adeyemo, Gregory C. DeAngelis, Dora E. Angelaki

Research output: Contribution to journalArticle

Abstract

Humans and monkeys use both vestibular and visual motion (optic flow) cues to discriminate their direction of self-motion during navigation. A striking property of heading perception from optic flow is that discrimination is most precise when subjects judge small variations in heading around straight ahead, whereas thresholds rise precipitously when subjects judge heading around an eccentric reference. We show that vestibular heading discrimination thresholds in both humans and macaques also show a consistent, but modest, dependence on reference direction. We used computational methods (Fisher information, maximum likelihood estimation, and population vector decoding) to show that population activity in area MSTd predicts the dependence of heading thresholds on reference eccentricity. This dependence arises because the tuning functions for most neurons have a steep slope for directions near straight forward. Our findings support the notion that population activity in extrastriate cortex limits the precision of both visual and vestibular heading perception.

Original languageEnglish (US)
Pages (from-to)596-609
Number of pages14
JournalNeuron
Volume66
Issue number4
DOIs
StatePublished - May 1 2010
Externally publishedYes

Keywords

  • Sysneuro

ASJC Scopus subject areas

  • Neuroscience(all)

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