Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban Haiti

T. B. Hallett, J. Aberle-Grasse, G. Bello, L. M. Boulos, M. P A Cayemittes, B. Cheluget, J. Chipeta, R. Dorrington, S. Dube, A. K. Ekra, J. M. Garcia-Calleja, G. P. Garnett, S. Greby, S. Gregson, J. T. Grove, S. Hader, J. Hanson, W. Hladik, S. Ismail, S. KassimW. Kirungi, L. Kouassi, A. Mahomva, L. Marum, C. Maurice, M. Nolan, T. Rehle, J. Stover, Neff Walker

Research output: Contribution to journalArticle

Abstract

Objective: To determine whether observed changes in HIV prevalence in countries with generalised HIV epidemics are associated with changes in sexual risk behaviour. Methods: A mathematical model was developed to explore the relation between prevalence recorded at antenatal clinics (ANCs) and the pattern of incidence of infection throughout the population. To create a null model a range of assumptions about sexual behaviour, natural history of infection, and sampling biases in ANC populations were explored to determine which factors maximised declines in prevalence in the absence of behaviour change. Modelled prevalence, where possible based on locally collected behavioural data, was compared with the observed prevalence data in urban Haiti, urban Kenya, urban Cote d'Ivoire, Malawi, Zimbabwe, Rwanda, Uganda, and urban Ethiopia. Results: Recent downturns in prevalence observed in urban Kenya, Zimbabwe, and urban Haiti, like Uganda before them, could only be replicated in the model through reductions in risk associated with changes in behaviour. In contrast, prevalence trends in urban Cote d'Ivoire, Malawi, urban Ethiopia, and Rwanda show no signs of changed sexual behaviour. Conclusions: Changes in patterns of HIV prevalence in urban Kenya, Zimbabwe, and urban Haiti are quite recent and caution is required because of doubts over the accuracy and representativeness of these estimates. Nonetheless, the observed changes are consistent with behaviour change and not the natural course of the HIV epidemic.

Original languageEnglish (US)
JournalSexually Transmitted Infections
Volume82
Issue numberSUPPL. 1
DOIs
StatePublished - Apr 2006
Externally publishedYes

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Haiti
Zimbabwe
Uganda
Kenya
Sexual Behavior
HIV
Rwanda
Cote d'Ivoire
Malawi
Ethiopia
Selection Bias
Risk Reduction Behavior
Risk-Taking
Infection
Population
Theoretical Models
Incidence

ASJC Scopus subject areas

  • Dermatology
  • Microbiology (medical)
  • Immunology

Cite this

Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban Haiti. / Hallett, T. B.; Aberle-Grasse, J.; Bello, G.; Boulos, L. M.; Cayemittes, M. P A; Cheluget, B.; Chipeta, J.; Dorrington, R.; Dube, S.; Ekra, A. K.; Garcia-Calleja, J. M.; Garnett, G. P.; Greby, S.; Gregson, S.; Grove, J. T.; Hader, S.; Hanson, J.; Hladik, W.; Ismail, S.; Kassim, S.; Kirungi, W.; Kouassi, L.; Mahomva, A.; Marum, L.; Maurice, C.; Nolan, M.; Rehle, T.; Stover, J.; Walker, Neff.

In: Sexually Transmitted Infections, Vol. 82, No. SUPPL. 1, 04.2006.

Research output: Contribution to journalArticle

Hallett, TB, Aberle-Grasse, J, Bello, G, Boulos, LM, Cayemittes, MPA, Cheluget, B, Chipeta, J, Dorrington, R, Dube, S, Ekra, AK, Garcia-Calleja, JM, Garnett, GP, Greby, S, Gregson, S, Grove, JT, Hader, S, Hanson, J, Hladik, W, Ismail, S, Kassim, S, Kirungi, W, Kouassi, L, Mahomva, A, Marum, L, Maurice, C, Nolan, M, Rehle, T, Stover, J & Walker, N 2006, 'Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban Haiti', Sexually Transmitted Infections, vol. 82, no. SUPPL. 1. https://doi.org/10.1136/sti.2005.016014
Hallett, T. B. ; Aberle-Grasse, J. ; Bello, G. ; Boulos, L. M. ; Cayemittes, M. P A ; Cheluget, B. ; Chipeta, J. ; Dorrington, R. ; Dube, S. ; Ekra, A. K. ; Garcia-Calleja, J. M. ; Garnett, G. P. ; Greby, S. ; Gregson, S. ; Grove, J. T. ; Hader, S. ; Hanson, J. ; Hladik, W. ; Ismail, S. ; Kassim, S. ; Kirungi, W. ; Kouassi, L. ; Mahomva, A. ; Marum, L. ; Maurice, C. ; Nolan, M. ; Rehle, T. ; Stover, J. ; Walker, Neff. / Declines in HIV prevalence can be associated with changing sexual behaviour in Uganda, urban Kenya, Zimbabwe, and urban Haiti. In: Sexually Transmitted Infections. 2006 ; Vol. 82, No. SUPPL. 1.
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AU - Hallett, T. B.

AU - Aberle-Grasse, J.

AU - Bello, G.

AU - Boulos, L. M.

AU - Cayemittes, M. P A

AU - Cheluget, B.

AU - Chipeta, J.

AU - Dorrington, R.

AU - Dube, S.

AU - Ekra, A. K.

AU - Garcia-Calleja, J. M.

AU - Garnett, G. P.

AU - Greby, S.

AU - Gregson, S.

AU - Grove, J. T.

AU - Hader, S.

AU - Hanson, J.

AU - Hladik, W.

AU - Ismail, S.

AU - Kassim, S.

AU - Kirungi, W.

AU - Kouassi, L.

AU - Mahomva, A.

AU - Marum, L.

AU - Maurice, C.

AU - Nolan, M.

AU - Rehle, T.

AU - Stover, J.

AU - Walker, Neff

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