Decline in semicircular canal and otolith function with age

Yuri Agrawal, Maria Geraldine Zuniga, Marcela Davalos-Bichara, Michael C Schubert, Jeremy D Walston, Jennifer Hughes, John P Carey

Research output: Contribution to journalArticle

Abstract

Objective: To characterize the physiologic nature of the vestibular dysfunction that occurs with the normative aging process. Study Design: Cross-sectional study. Setting: Tertiary care academic medical center. Patients: Fifty individuals age 70 years and above. INTERVENTIONS: Head thrust dynamic visual acuity testing and cervical and ocular vestibular-evoked myogenic potential (VEMP) testing. Main Outcome Measures: Semicircular canal function measured by head thrust dynamic visual acuity testing in each of the 3 semicircular canal planes, and saccular and utricular function measured by cervical VEMP and ocular VEMP testing, respectively. Results: We observed significant declines in semicircular canal function in each of the canal planes as well as otolith function associated with aging. We found that individuals with impaired horizontal and superior semicircular canal function also were likely to have concomitant deficits in utricular but not saccular function. Overall, we noted that the prevalence of semicircular canal dysfunction was highest followed by saccular then utricular impairment, although we did observe individuals with isolated otolith deficits. Conclusion: These data suggest an overall decline in semicircular canal as well as otolith function associated with aging, although the magnitude of impairment was greater for the semicircular canals than the otoliths in this elderly population. A better understanding of the specific vestibular deficits that occur with aging can inform the development of rational screening, vestibular rehabilitation, and fall risk reduction strategies in older individuals.

Original languageEnglish (US)
Pages (from-to)832-839
Number of pages8
JournalOtology and Neurotology
Volume33
Issue number5
DOIs
StatePublished - Jul 2012

Fingerprint

Otolithic Membrane
Semicircular Canals
Vestibular Evoked Myogenic Potentials
Visual Acuity
Head
Tertiary Healthcare
Risk Reduction Behavior
Rehabilitation
Cross-Sectional Studies
Outcome Assessment (Health Care)

Keywords

  • Aging
  • Otolith
  • Semicircular canal
  • Vestibular dysfunction

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Clinical Neurology
  • Sensory Systems
  • Medicine(all)

Cite this

Decline in semicircular canal and otolith function with age. / Agrawal, Yuri; Zuniga, Maria Geraldine; Davalos-Bichara, Marcela; Schubert, Michael C; Walston, Jeremy D; Hughes, Jennifer; Carey, John P.

In: Otology and Neurotology, Vol. 33, No. 5, 07.2012, p. 832-839.

Research output: Contribution to journalArticle

Agrawal, Yuri ; Zuniga, Maria Geraldine ; Davalos-Bichara, Marcela ; Schubert, Michael C ; Walston, Jeremy D ; Hughes, Jennifer ; Carey, John P. / Decline in semicircular canal and otolith function with age. In: Otology and Neurotology. 2012 ; Vol. 33, No. 5. pp. 832-839.
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