DCC probes, primers, and kits

Bert Vogelstein

doi:10.1016/s0734-9750(97)87771-3

DCC probes, primers, and kits

Bert Vogelstein

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

A new human gene termed DCC is disclosed. Methods and kits are provided for assessing mutations of the DCC gene in human tissues and body samples. Insertion, deletion, and point mutations in DCC are observed in human tumor cells. Normal tissues express DCC while most colorectal cancers do not. Loss of wild-type DCC genes is associated with neoplastic progression and a diminished life expectancy.

Original language	English (US)
Pages (from-to)	734
Number of pages	1
Journal	Biotechnology Advances
Volume	15
Issue number	3-4
DOIs	https://doi.org/10.1016/s0734-9750(97)87771-3
State	Published - 1997

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

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10.1016/s0734-9750(97)87771-3

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title = "DCC probes, primers, and kits",

abstract = "A new human gene termed DCC is disclosed. Methods and kits are provided for assessing mutations of the DCC gene in human tissues and body samples. Insertion, deletion, and point mutations in DCC are observed in human tumor cells. Normal tissues express DCC while most colorectal cancers do not. Loss of wild-type DCC genes is associated with neoplastic progression and a diminished life expectancy.",

author = "Bert Vogelstein",

year = "1997",

doi = "10.1016/s0734-9750(97)87771-3",

language = "English (US)",

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AU - Vogelstein, Bert

PY - 1997

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N2 - A new human gene termed DCC is disclosed. Methods and kits are provided for assessing mutations of the DCC gene in human tissues and body samples. Insertion, deletion, and point mutations in DCC are observed in human tumor cells. Normal tissues express DCC while most colorectal cancers do not. Loss of wild-type DCC genes is associated with neoplastic progression and a diminished life expectancy.

AB - A new human gene termed DCC is disclosed. Methods and kits are provided for assessing mutations of the DCC gene in human tissues and body samples. Insertion, deletion, and point mutations in DCC are observed in human tumor cells. Normal tissues express DCC while most colorectal cancers do not. Loss of wild-type DCC genes is associated with neoplastic progression and a diminished life expectancy.

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DO - 10.1016/s0734-9750(97)87771-3

M3 - Article

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SN - 0734-9750

VL - 15

SP - 734

JO - Biotechnology Advances

JF - Biotechnology Advances

IS - 3-4

ER -

DCC probes, primers, and kits

Abstract

ASJC Scopus subject areas

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