DCC probes, primers, and kits

Research output: Contribution to journalArticlepeer-review


A new human gene termed DCC is disclosed. Methods and kits are provided for assessing mutations of the DCC gene in human tissues and body samples. Insertion, deletion, and point mutations in DCC are observed in human tumor cells. Normal tissues express DCC while most colorectal cancers do not. Loss of wild-type DCC genes is associated with neoplastic progression and a diminished life expectancy.

Original languageEnglish (US)
Pages (from-to)734
Number of pages1
JournalBiotechnology Advances
Issue number3-4
StatePublished - 1997

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


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