@article{8d918dd41936478fb872e34771f42011,
title = "Data management and data quality in PERCH, a large international case-control study of severe childhood pneumonia",
abstract = "The Pneumonia Etiology Research for Child Health (PERCH) study is the largest multicountry etiology study of pediatric pneumonia undertaken in the past decades. The study enrolled 423hospitalized cases and 532controls over years across research sites in countries in Africa and Asia. The volume and complexity of data collection in PERCH presented considerable logistical and technical challenges. The project chose an internet-based data entry system to allow real-time access to the data, enabling the project to monitor and clean incoming data and perform preliminary analyses throughout the study. To ensure high-quality data, the project developed comprehensive quality indicator, data query, and monitoring reports. Among the approximately 900cases and controls, analyzable laboratory results were available for =96% of core specimens collected. Selected approaches to data management in PERCH may be extended to the planning and organization of international studies of similar scope and complexity.",
keywords = "Data management, Data quality, Electronic data capture, PERCH",
author = "Watson, {Nora L.} and Christine Prosperi and Driscoll, {Amanda J.} and Higdon, {Melissa M.} and Park, {Daniel E.} and Megan Sanza and DeLuca, {Andrea N.} and Awori, {Juliet O.} and Doli Goswami and Emily Hammond and Lokman Hossain and Catherine Johnson and Alice Kamau and Locadiah Kuwanda and Moore, {David P.} and Omid Neyzari and Uma Onwuchekwa and David Parker and Patranuch Sapchookul and Phil Seidenberg and Arifin Shamsul and Kazungu Siazeele and Prasong Srisaengchai and Mamadou Sylla and Levine, {Orin S.} and Murdoch, {David R.} and O'Brien, {Katherine L.} and Mark Wolff and Knoll, {Maria Deloria}",
note = "Funding Information: Supplement sponsorship. This article appears as part of the supplement “Pneumonia Etiology Research for Child Health (PERCH): Foundational Basis for the Primary Etiology Results,” sponsored by a grant from the Bill & Melinda Gates Foundation to the PERCH study of Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. Funding Information: Financial support. This work was supported by the Bill & Melinda Gates Foundation (grant number 48968 to the International Vaccine Access Center, Department of International Health, Johns Hopkins Bloomberg School of Public Health). Funding Information: Potential conflicts of interest. M. D. K. has received funding for consulting from Merck, Pfizer, and Novartis, and grant funding from Merck. All other authors report no potential conflicts. K. L. O. has received grant funding from GSK and Pfizer and participates on technical advisory boards for Merck, Sanofi Pasteur, PATH, Affinivax, and ClearPath. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed. Publisher Copyright: {\textcopyright} The Author 2017.",
year = "2017",
doi = "10.1093/cid/cix080",
language = "English (US)",
volume = "64",
pages = "S238--S244",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
}