TY - JOUR
T1 - Data for action
T2 - Collection and use of local data to end tuberculosis
AU - Theron, Grant
AU - Jenkins, Helen E.
AU - Cobelens, Frank
AU - Abubakar, Ibrahim
AU - Khan, Aamir J.
AU - Cohen, Ted
AU - Dowdy, David W.
N1 - Funding Information:
We are supported by the Wellcome Trust ( grant WT099854MA ) and a South African Medical Research Council Career Development Award (to GT); the US National Institutes of Health (K01AI102944, awarded to HEJ; R01AI112438 awarded to TC); the B Frank and Kathleen Polk Assistant Professorship in Epidemiology (to DWD); and the UK National Institute of Health Research, Medical Research Council, and Public Health England (IA). The funders had no role in the conception, preparation, review, approval, or submission of this manuscript. The content is solely the responsibility of the authors and does not necessarily represent the views of the US National Institute of Allergy and Infectious Diseases or the US National Institutes of Health. We thank Carole Mitnick for her review and the important comments she contributed during drafting and Carly Rodriguez for coordination and research assistance in the preparation of this manuscript.
Publisher Copyright:
© 2015 Elsevier Ltd.
PY - 2015/12/5
Y1 - 2015/12/5
N2 - Accelerating progress in the fight against tuberculosis will require a drastic shift from a strategy focused on control to one focused on elimination. Successful disease elimination campaigns are characterised by locally tailored responses that are informed by appropriate data. To develop such a response to tuberculosis, we suggest a three-step process that includes improved collection and use of existing programmatic data, collection of additional data (eg, geographic information, drug resistance, and risk factors) to inform tailored responses, and targeted collection of novel data (eg, sequencing data, targeted surveys, and contact investigations) to improve understanding of tuberculosis transmission dynamics. Development of a locally targeted response for tuberculosis will require substantial investment to reconfigure existing systems, coupled with additional empirical data to evaluate the effectiveness of specific approaches. Without adoption of an elimination strategy that uses local data to target hotspots of transmission, ambitious targets to end tuberculosis will almost certainly remain unmet.
AB - Accelerating progress in the fight against tuberculosis will require a drastic shift from a strategy focused on control to one focused on elimination. Successful disease elimination campaigns are characterised by locally tailored responses that are informed by appropriate data. To develop such a response to tuberculosis, we suggest a three-step process that includes improved collection and use of existing programmatic data, collection of additional data (eg, geographic information, drug resistance, and risk factors) to inform tailored responses, and targeted collection of novel data (eg, sequencing data, targeted surveys, and contact investigations) to improve understanding of tuberculosis transmission dynamics. Development of a locally targeted response for tuberculosis will require substantial investment to reconfigure existing systems, coupled with additional empirical data to evaluate the effectiveness of specific approaches. Without adoption of an elimination strategy that uses local data to target hotspots of transmission, ambitious targets to end tuberculosis will almost certainly remain unmet.
UR - http://www.scopus.com/inward/record.url?scp=84949527433&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84949527433&partnerID=8YFLogxK
U2 - 10.1016/S0140-6736(15)00321-9
DO - 10.1016/S0140-6736(15)00321-9
M3 - Review article
C2 - 26515676
AN - SCOPUS:84949527433
SN - 0140-6736
VL - 386
SP - 2324
EP - 2333
JO - The Lancet
JF - The Lancet
IS - 10010
ER -