DAILY VARIATIONS OF MARROW AND SPLENIC ERYTHROPOIESIS, PINNA EPIDERMAL CELL MITOSIS AND PHYSICAL ACTIVITY IN C57Bl/6J MICE

Saul J. Sharkis, John D. Palmer, Judith Goodenough, Joseph LoBue, Albert S. Gordon

Research output: Contribution to journalArticlepeer-review

Abstract

Regular daily fluctuations in spontaneous physical activity and in the mitotic indices of marrow and splenic erythroid elements and pinna cells, were observed. Both male and female C57Bl/6J mice showed these rhythms. Of particular interest was the finding that the spleen and the marrow mitotic activity showed a reciprocal relationship. The role of several hormones and the biological clock in control of these rhythms are discussed.

Original languageEnglish (US)
Pages (from-to)381-387
Number of pages7
JournalCell Proliferation
Volume7
Issue number4
DOIs
StatePublished - Jul 1974

ASJC Scopus subject areas

  • Cell Biology

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