DAILY VARIATIONS OF MARROW AND SPLENIC ERYTHROPOIESIS, PINNA EPIDERMAL CELL MITOSIS AND PHYSICAL ACTIVITY IN C57Bl/6J MICE

Saul J. Sharkis, John D. Palmer, Judith Goodenough, Joseph LoBue, Albert S. Gordon

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Regular daily fluctuations in spontaneous physical activity and in the mitotic indices of marrow and splenic erythroid elements and pinna cells, were observed. Both male and female C57Bl/6J mice showed these rhythms. Of particular interest was the finding that the spleen and the marrow mitotic activity showed a reciprocal relationship. The role of several hormones and the biological clock in control of these rhythms are discussed.

Original languageEnglish (US)
Pages (from-to)381-387
Number of pages7
JournalCell Proliferation
Volume7
Issue number4
DOIs
StatePublished - Jul 1974

ASJC Scopus subject areas

  • Cell Biology

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