Daily exercise reduces measures of heart rate and blood pressure variability in hypertensive rats

S. E. DiCarlo; H. L. Collins; D. W. Rodenbaugh; M. R. Smitha; R. D. Berger; V. K. Yeragani

doi:10.1081/CEH-120003202

Daily exercise reduces measures of heart rate and blood pressure variability in hypertensive rats

S. E. DiCarlo, H. L. Collins, D. W. Rodenbaugh, M. R. Smitha, R. D. Berger, V. K. Yeragani

School of Medicine

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

This study was designed to test the hypothesis that daily spontaneous running (DSR) reduces measures of heart rate and blood pressure variability in spontaneously hypertensive rats (SHR). After 8 weeks of DSR or sedentary control, rats were chronically instrumented with arterial catheters. Daily exercise reduced most measures of heart rate (HR) and blood pressure variability. Specifically DSR decreased heart rate, Low Frequency Power (LF: 0.19-0.61 Hz), and Low Frequency/High Frequency (HF: 1.2-2.5 Hz) ratio of HR. Furthermore, Total Power (TP), LF power, and LF/HF ratio of systolic blood pressure were reduced by daily spontaneous running. Finally, TP, LF and HF powers and LF/HF ratios of diastolic blood pressure were reduced by daily spontaneous running. These data demonstrate that daily exercise reduces sympathetic activity and possibly increases cardiac reserve in hypertensive animals.

Original language	English (US)
Pages (from-to)	221-234
Number of pages	14
Journal	Clinical and Experimental Hypertension
Volume	24
Issue number	3
DOIs	https://doi.org/10.1081/CEH-120003202
State	Published - 2002

Keywords

Exercise training
Hypertension
Power spectral analysis

ASJC Scopus subject areas

Internal Medicine
Physiology

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10.1081/CEH-120003202

Cite this

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title = "Daily exercise reduces measures of heart rate and blood pressure variability in hypertensive rats",

abstract = "This study was designed to test the hypothesis that daily spontaneous running (DSR) reduces measures of heart rate and blood pressure variability in spontaneously hypertensive rats (SHR). After 8 weeks of DSR or sedentary control, rats were chronically instrumented with arterial catheters. Daily exercise reduced most measures of heart rate (HR) and blood pressure variability. Specifically DSR decreased heart rate, Low Frequency Power (LF: 0.19-0.61 Hz), and Low Frequency/High Frequency (HF: 1.2-2.5 Hz) ratio of HR. Furthermore, Total Power (TP), LF power, and LF/HF ratio of systolic blood pressure were reduced by daily spontaneous running. Finally, TP, LF and HF powers and LF/HF ratios of diastolic blood pressure were reduced by daily spontaneous running. These data demonstrate that daily exercise reduces sympathetic activity and possibly increases cardiac reserve in hypertensive animals.",

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AU - DiCarlo, S. E.

AU - Collins, H. L.

AU - Rodenbaugh, D. W.

AU - Smitha, M. R.

AU - Berger, R. D.

AU - Yeragani, V. K.

PY - 2002

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KW - Hypertension

KW - Power spectral analysis

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Daily exercise reduces measures of heart rate and blood pressure variability in hypertensive rats

Abstract

Keywords

ASJC Scopus subject areas

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