Daily exercise reduces measures of heart rate and blood pressure variability in hypertensive rats

S. E. DiCarlo, H. L. Collins, D. W. Rodenbaugh, M. R. Smitha, Ronald D Berger, V. K. Yeragani

Research output: Contribution to journalArticle

Abstract

This study was designed to test the hypothesis that daily spontaneous running (DSR) reduces measures of heart rate and blood pressure variability in spontaneously hypertensive rats (SHR). After 8 weeks of DSR or sedentary control, rats were chronically instrumented with arterial catheters. Daily exercise reduced most measures of heart rate (HR) and blood pressure variability. Specifically DSR decreased heart rate, Low Frequency Power (LF: 0.19-0.61 Hz), and Low Frequency/High Frequency (HF: 1.2-2.5 Hz) ratio of HR. Furthermore, Total Power (TP), LF power, and LF/HF ratio of systolic blood pressure were reduced by daily spontaneous running. Finally, TP, LF and HF powers and LF/HF ratios of diastolic blood pressure were reduced by daily spontaneous running. These data demonstrate that daily exercise reduces sympathetic activity and possibly increases cardiac reserve in hypertensive animals.

Original languageEnglish (US)
Pages (from-to)221-234
Number of pages14
JournalClinical and Experimental Hypertension
Volume24
Issue number3
DOIs
StatePublished - 2002

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Running
Heart Rate
Blood Pressure
Inbred SHR Rats
Catheters

Keywords

  • Exercise training
  • Hypertension
  • Power spectral analysis

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Daily exercise reduces measures of heart rate and blood pressure variability in hypertensive rats. / DiCarlo, S. E.; Collins, H. L.; Rodenbaugh, D. W.; Smitha, M. R.; Berger, Ronald D; Yeragani, V. K.

In: Clinical and Experimental Hypertension, Vol. 24, No. 3, 2002, p. 221-234.

Research output: Contribution to journalArticle

DiCarlo, S. E. ; Collins, H. L. ; Rodenbaugh, D. W. ; Smitha, M. R. ; Berger, Ronald D ; Yeragani, V. K. / Daily exercise reduces measures of heart rate and blood pressure variability in hypertensive rats. In: Clinical and Experimental Hypertension. 2002 ; Vol. 24, No. 3. pp. 221-234.
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