Cytosine to thymine transitions from decay of cytosine-5-3H in bacteriophage S13

Fred Funk, Stanley Person

Research output: Contribution to journalArticle

Abstract

Decay of cytosine-5-3H incorporated into bacteriophage S13 DNA causes a molecular rearrangement of the cytosine molecule undergoing the decay. The molecular rearrangement produces a cytosine to thymine coding change with an efficiency approaching one. Decay of either thymidine-(methyl)-3H or cytosine-6-3H is less than 1 percent as effective in causing either cytosine to thymine or thymine to cytosine transitions.

Original languageEnglish (US)
Pages (from-to)1629-1631
Number of pages3
JournalScience
Volume166
Issue number3913
DOIs
StatePublished - Jan 1 1969

ASJC Scopus subject areas

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