Cytomegaloviruses: Simian Cytomegaloviruses

D. J. Alcendor, G. S. Hayward

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Probably all nonhuman primates harbor ubiquitous but largely inapparent latent or persistent infections with host-species-specific cytomegaloviruses (CMVs). Research with CMVs from chimpanzee, rhesus macaque, baboon, African green monkey, and tree shrew has revealed many similarities to and differences from the better-studied human CMV. All primate CMVs are classified in genus Cytomegalovirus in the subfamily Betaherpesvirinae of the family Herpesviridae, and are typified by the formation of large nuclear and cytoplasmic inclusion bodies in lytically infected cells. Aspects of the gene content, gene expression, and growth in cell culture of these viruses are described.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Virology
PublisherElsevier Ltd
Pages634-642
Number of pages9
ISBN (Print)9780123744104
DOIs
StatePublished - Jan 1 2008

Keywords

  • Adaptation to cell culture
  • Cytomegalovirus
  • Genome variation
  • Host specificity
  • Latent infection
  • Persistent infection
  • Plaque assays
  • Primate

ASJC Scopus subject areas

  • Immunology and Microbiology(all)

Fingerprint Dive into the research topics of 'Cytomegaloviruses: Simian Cytomegaloviruses'. Together they form a unique fingerprint.

Cite this