Cytomegalovirus antibody in cerebrospinal fluid of schizophrenic patients detected by enzyme immunoassay

E. Fuller Torrey, Robert H. Yolken, C. Jack Winfrey

Research output: Contribution to journalArticle

Abstract

By means of enzyme immunoassay techniques to detect the presence of antibody to cytomegalovirus, the cerebrospinal fluid of 178 patients with schizophrenia, 17 patients with bipolar disorders, and 11 other psychiatric patients was compared with that of 79 neurological patients and 41 normal control subjects. The cerebrospinal fluid of 20 of the schizophrenic patients and 3 of the patients with bipolar disorders showed significant increases in immunoglobulin M antibody to cytomegalovirus; no difference was found in patients on or off psychotropic medications.

Original languageEnglish (US)
Pages (from-to)892-894
Number of pages3
JournalScience
Volume216
Issue number4548
DOIs
StatePublished - Jan 1 1982

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