Abstract
The cytologic findings on cerebrospinal fluid examination of cervical chordoma in a 2-year-old girl are presented. The major cell type was a small, isolated, hyperchromatic cell with sharply defined nuclear membrane and granular cytoplasm. However, the characteristic cell of this neoplasm, the so-called physaliferous cell with typical bubbly cytoplasm, was also noted. Cytologic findings were compared to biopsy findings, with a good correlation of tumor morphology. Clinical follow-up revealed unusually aggressive tumor behavior, and the patient died a year later despite intensive chemotherapy. The differential diagnosis of the condition is also discussed.
Original language | English (US) |
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Pages (from-to) | 766-769 |
Number of pages | 4 |
Journal | Acta cytologica |
Volume | 39 |
Issue number | 4 |
State | Published - 1995 |
Externally published | Yes |
Keywords
- cerebrospinal fluid
- chordoma
- neck neoplasms
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology